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Americans Disabled By Vaccines
Uniting Victims of Autism, Guillain-Barré, Gardasil Syndrome, Gulf War Syndrome, Lyme Disease, and more.

Phillips-Offit-Wakefield Syndrome / SIIDS / Gardasil Syndrome

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PHILLIPS-OFFIT-WAKEFIELD Syndrome, Type 1

BACKGROUND

In 2010 I was asked by a reporter to investigate several families whose children reportedly suffered adverse effects from the Gardasil HPV vaccine. This research is still ongoing today. Not only have these children and adults contributed greatly to medical research, they have given a voice to autism. Virtually all these study participants have the same or similar genetic mutations and/or alleles, and share the same core symptoms and similar pathogens, which vary little, except for intensity.  Many of these children have medical conditions which would prevent them from participating in HPV Vaccine Clinical Trials, called Exclusion Criteria. Allergies, asthma, and other conditions are listed under the heading of EXCLUSION CRITERIA in the "MOTHER-DAUGHTER INITIATIVE..... ." This is just one of many Gardasil Clinical Trials. Because children and families with allergies and other (autoimmune) conditions were purposefully excluded during Clinical Trials, the actual SAFETY and EFFECTIVENESS of the GARDASIL HPV Vaccine is highly questionable, because greater than 50% of children in the United States have allergies according to the CDC (.pdf file from CDC).

 

INTRODUCTION

Immunization has anecdotally contributed to the health of mankind, and has reportedly stopped plagues. However, the recent increase in the quantity of vaccines given to children with developing brains, in addition to the increase in strength of chemical "adjuvant" needed to hypersensitize the human immune system in order to produce antibodies to single proteins that are now being used in genetically modified vaccines (recombinant vaccines), has increased the autism rate in the United States by 10,000 times since the 1960s. A prime example of this is the isolation of the island of Cuba by the United States. During the Embargo, the Cuban Government took over the healthcare of its people, but Cuban Lifespan kept pace with the United States. From the 1960s to the present, Pediatricians in the United States formed labor organizations, such as the American Academy of Pediatrics (AAP), which Dr. Lucas quotes as being founded during the height of prohibition by 35 doctors sitting around drinking scotch "well into the wee hours of the morning." The first goal listed was to make alliances with groups, such as pharmaceutical companies, and the second goal, 'to encourage pediatric clinical and laboratory investigation,' appears to have been replaced by hypothetical doctors such as Paul Offit, who relies on Melvin Cohn, a theoretical immunologist. Dr. Paul Offit now claims that you can safely inject 5 liters of vaccine into an infant at one time, while Dr. Gaston Ramon, a French immunologist who reportedly coined the term "adjuvant," warned in peer reviewed and published research in 1926, that an infection or multiple antigens from other vaccines, result in an unpredictably high immune response and antibodies. At the same time, pharmaceutical entrepreneurs such as MERCK & Co. spent $100,000,000.00 on a single pre-rollout campaign to convince parents that  their Gardasil HPV vaccine would prevent cervical cancer. MERCK also has groups that track social media posts that are unfavorable to their products, especially the Gardasil HPV vaccine. These groups stalk and harass parents of children who died because of their products, and are responsible for most of the 5000 posts prior to the airing of a Katie Couric Show about one of the many girls who died after receiving the Gardasil HPV vaccine. MERCK downplays the fact that their last major FDA approved drug, VIOXX, had reportedly caused an estimated 180,000 heart attacks, and Billions of dollars in lawsuits for MERCK CEO Kenneth Frazier, who is a Lawyer, not a doctor. MERCK won an award for their advertising campaign for Gardasil. The worth of MERCK now exceeds $100,000,000,000.00 ($100 BILLION Dollars). Pharmaceutical companies now began campaigns to "prevent childhood diseases" by injecting copies in part or in whole of a virus, bacteria, or other pathogen, while Cuba did not. The World Health Organization and its board of doctors and pharmaceutical companies pushed countries to vaccinate whole populations. In 2009, the World Health Organization declared that South Korea was free of Measles after a mass vaccination campaign of schoolchildren. In 2011, Harvard Medical Researchers found that 1 in 38 South Korean schoolchildren now had symptoms of Autism. While much of the world, especially the United States and its mandated vaccine schedules, continued to increase the quantity and strength of its vaccines, Cuba did not. Cuban lifespan kept pace with the United States, and Cuba has become an international vacation destination for the world. The Cuban government gave young children 11 vaccines, 8 of which were manufactured in Cuba. At the same time, many American adults are being forced to be vaccinated if they want to keep their jobs, while American children are being forced to be vaccinated if they want an education, and are being turned away and are denied medical care by Pediatricians if their parents don't buy vaccines and/or other products that they sell or prescribe. As a result, the Autism rate in Cuba remained at the 1960 rate of 1 in 60,000 children. The Autism rate in the United States exploded to around 1 in 42 for male children according to new research published in the Washington Post in 2015, and slightly less for girls, and the CDC reports that 1 in 6 children in the United States has developmental delays. The group, Autism Speaks, reports that each autistic child costs a family $60,000.00 per year, much of which goes to pediatricians and pharmaceutical companies.

PROPOSED ABSTRACT

Children and adults who carry the Human Leukocyte Antigen DRB1 (HLA-DRB1), or similar Haplotype, such as HLA-DR/DQ/B-27/etc., are at risk of suffering adverse affects if vaccinated. However, if the patient has been exposed to Tick-Borne Diseases and also presents with symptoms of Ehlers-Danlos Syndrome, Type 3 (Hypermobility), and has Native American ancestors, the person is at great risk of suffering severe or life-threatening adverse reactions to a vaccine, especially recombinant vaccines which require a strong adjuvant. If the person also has asthma, death may occur within hours (Meredith Prohaska, 12yr old female from Wisconsin), or weeks  (Michael Fisher, 15yr old male from Pennsylvania) following a vaccination, injury, or medical procedure. The syndrome is characterized by:
1). Quick onset 25(OH)vit-D deficiency which may result in bone demineralization and inhibited Membrane Attack Complex
2). Activation and/or reactivation and virulence of MULTIPLE latent or dormant pathogens
3). Low INTRACELLULAR magnesium may present as irritability, mood swings, jerky or involuntary muscle movements, and sometimes Panic Disorder, Postural Tachycardia Syndrome, and heart palpitations
4). Joint, nerve, and/or chest pain. Chest pain is reported by > 80% of study participants
5). Hyperephesia, which may typically include sensitivity to light (photophobia), sound, or feeling of pain on areas of skin
6). Fatigue
7). Head Pressure, typically sometimes debilitating, often lasting for days, weeks, or months
8). Interstitial Cystitis has been reported, ranging from several months to two years after the Gardasil HPV vaccination

Note: If the person is an infant, or has a developing brain,  H3K4 Trimethylation inhibition may result in Semaphorin 3 and 5 disruption, which may contribute to impaired axon production and proliferation, which is critical for cognitive development. This axon/neuron impairment may result in Autism Spectrum Disorder. Disruption of Semaphorin 7 is associated with Leukemia and possibly other cancers in recent peer reviewed and published research.

 

PATHOPHYSIOLOGY HIGHLIGHTS (SYNOPSIS) 

Children and adults who carry the HLA-DRB1 or similar Genetic Haplotype are believed to have ancestors who lived in, or traveled to, areas with high levels of pathogens (germs). These children and adults typically report that they are active and rarely get sick. Today we call this "IMMUNE TOLERANCE," which is typically a throttling back of the Major Histocompatibility Complex of the immune system.  This causes these people to appear healthy and active, but they may carry a high pathogen load, including dormant pathogens. 

This unique immune tolerance appears to keep pathogens under control by allowing dominant pathogens, such as Epstein Barr Virus, to survive and keep the less virulent pathogens under control, much like an alpha wolf controls the rest of the wolf pack. This higher pathogen load can evoke an unpredictably high immune response if these children and adults are vaccinated. This phenomenon  was first reported by the father of modern vaccines, GASTON RAMON, in 1926.  Gaston Ramon coined the term "ADJUVANT," which is still used today to describe the chemical in a vaccine used to stimulate the immune system.  Gaston Ramon experimented with animals by adding infectious pathogens, and even tapioca, to vaccines to produce a greater immune response. Unfortunately, profit-motivated "quacks" like Dr. Paul Offit, fraudulently ignore facts and tell parents that vaccines are safe for everyone, similar to the "unsinkable" TITANIC. 

In my five year study, I observed that vaccines elicited a hyperactive and unpredictable immune response in humans which resulted in multiple life-threatening reactions or even death. I observed that children who were asthmatic appeared to have an increased risk of death from a vaccination, as in the case of 12 yr old Meredith Prohaska and 15 yr old Michael Fisher, both of whom were asthmatic (allergy to mold), but were vaccinated anyway. Vaccinating children with allergies was forbidden in Clinical Trials (EXCLUSION CRITERIA), such as the MOTHER-DAUGHTER INITIAVE.  I observed that this hyper-activation resulted in a massive attack against pathogens by the immune system. Part of this attack consisted of inflammatory cytokines, which inflamed the gut and caused a disruption of the mucosal lining of the intestines.  Unfortunately this disruption of the protective mucosal lining of the gut allowed food proteins passing through the gut to come into contact with immune cells in the lining of the gut, which appeared to result in ever increasing food allergies, which may result in a HISTAMINE INTOLERANCE, followed by IBS, followed by Gastroparesis if left untreated. It appears that this vaccine-induced systemic inflammation may also contribute to inflamed glial cells, which may affect nearby myelin-producing Oligodendrocytes, which may help account for the MS-like symptoms I observed, and which may contribute to other myelin degenerative disorders such as MS, in addition to causing the  disruption of Gap Junctions, including those in the brain (http://www.ncbi.nlm.nih.gov/pubmed/24582000), especially since new research proves that Polysorbate-80 coated (vaccine) nanoparticles have been shown capable of delivering drugs right through the blood brain barrier, and deep into the brain (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC539316/). The slurry of toxins (lysoming) created by cell apoptosis appeared to result in a sepsis-like condition that appears to exceed the liver's filtering capacity, exacerbated by genetic mutations, especially those mutations associated with the CYP450 Pathway in these children. The liver is responsible for synthesizing vitamin D. Dietary fats and carbohydrates now appear to form a bottleneck in CYP450, which rendered many CYP450 metabolized medications useless, and further inhibited the liver. This also appeared to be part of the failure mechanism that inhibited the liver from synthesizing Vitamin D.  A vitamin D deficiency was observed in all subjects in this group. Vitamin D deficiency, 25[OH]VitD <30 ng/ml, is a key symptom for identifying this syndrome. With the inhibition of the MEMBRANE ATTACK COMPLEX (MAC), due to insufficient Vitamin D to make C5, the immune system was compromised, and the reactivation and virulence of latent pathogens was now observed. (http://www.ncbi.nlm.nih.gov/pubmed/24919177).  LabCorp Western Blot Panels were CDC Positive for Borrelia Burgdorferi (Lyme Disease) in a significant number of subjects, with Bartonella, Babesia, Mycoplasma, Coxsackie, Protomyxzoa Rheumatica (formerly FL1953), various Human Herpes Viruses (HHVs), Epstein Barr Virus (including three cases of CAEBV), plus much more were present.  I observed that the liver of these subjects was also typically genetically compromised due to GSTM1 or other genetic mutation or polymorphism.  Inflammation-induced malabsorption and the inability of the liver to efficiently filter blood and produce sufficient metabolites and micronutrients may contribute to, or be the cause of autism in infants and toddlers, due to vaccine-induced disruption of Methylation, Transsulfuration, and other metabolic Cycles, such as H3K4 Tri-Methylation, where the resulting Semaphorins have been documented to be responsible for such things as AXON cone guidance and proliferation. Semaphorin deficiencies may contribute to various cancers  (http://www.ncbi.nlm.nih.gov/pubmed/15569615).  Semaphorins also control fibroblasts that can make Leukemia resistant to chemotherapy http://www.sciencedirect.com/science/article/pii/S1084952112001851.  Semaphorin 5A (SEMA5A) was recently (2014) found to inhibit Synaptogenesis, a key contributor to autism (reference: http://elifesciences.org/content/3/e04390 *and* http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055433/ ).  Experimentally increasing the production of Semaphorin 3A and 3C in grafted dopamine neurons has provided experimental recovery from Parkinson's Disease (http://www.ncbi.nlm.nih.gov/pubmed/23732989). The potentially deadly hyper-activation of the immune system that I observed was first documented and Published by GASTON RAMON, a French Veterinarian, in 1926 (reference: http://www.nature.com/icb/journal/v82/n5/full/icb200475a.html ).

Any Pediatrician or medical entity who disrupts the production of Semaphorins by willfully or negligently vaccinating a child with an infection, should be held accountable in a court of law, and if that child develops autism or cancer, the death penalty should be considered by the court.


FIVE YEAR STUDY AND ANALYSIS OF ADVERSE REACTIONS
TO THE GARDASIL HPV VACCINE

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Copyright© Lloyd W. Phillips, 2015
PPL@MAILBOX7.NET
Phone 336-600-1055

ABSTRACT

Recombinant vaccines, such as HepB, MMR, and the Gardasil HPV vaccine, require a very potent adjuvant and may elicit an unpredictably high immune response in a host with an elevated pathogen load, especially in families who carry the with the HLA-DRB1, HLA-B27, HLA-DR/DQ, HLA-DR15, or similar genetic haplotype. In a group of approximately 400 patients to date, we have observed that the higher pathogen load in these children and adults may evoke an unpredictably high immune response that causes the mucosal lining of the gut to become compromised, allowing food proteins to contact hyperactivated immune cells in the epithelial lining of the gut. This appears to produce new or enhanced allergies to food proteins. At the same time, I observed that the Gardasil qHPV vaccine reactivated multiple dormant pathogens, which became virulent, resulting in debilitating Chronic Illness. A 2014 peer reviewed and published abstract confirmed our findings: DOI: 10.1371/journal.pone.0098819.  I then observed that the liver was not capable of properly filtering the blood when the immune system became hyperactivated, and attempted to kill the higher amounts of active and/or dormant infections in the children who had an immune condition called TOLERANCE, typically due to the HLA-DRB1 or similar Haplotype.

The children and adults who became ill with this syndrome, typically reported they rarely got sick before being vaccinated. The key to this syndrome is the higher latent (dormant) pathogen loads in the body caused by the HLA-DRB1 or similar haplotype in these patients, together with the decreased efficiency of the liver, typically found to be caused by genetic mutations, typically involving a Glutathione S-Transferase Deficiency, often caused by a GSTM1 or similar genetic mutation. The key to genetic mutations is NOT to look for a single gene, but to look for the presence of a member belonging to that family.

The final piece in this puzzle involves the vaccine-induced hyperactivated immune system causing apoptosis from multiple pathogens throughout the body, and the slurry of toxins from these lysoming cells, causing a sepsis-like condition that overwhelms and exceeds the genetically compromised liver's ability to filter. The liver is responsible for synthesizing Vitamin D, so an acute vitamin D deficiency will ALWAYS be one of the first symptoms for this Syndrome. As more and more food proteins contact immune cells, mast cells produced more and more histamine. Histamine Intolerance and Postural Orthostatic Tachycardia Syndrome, caused by histamine-dilated blood vessels, were the second most noted severe symptoms in this study group, which typically resulted in malabsorption and constipation.

Failure of Vitamin D synthesis in the liver results in a compromised immune system, because Vitamin D is a key component for Compliment 5 (C5), which is required by the MEMBRANE ATTACK COMPLEX, which hunts down and ruptures membranes of pathogen-infected cells.

It has recently been confirmed by peer-reviewed and published abstracts that surfactants, such as Polysorbate 80, can be used to coat and transport pharmaceutical drugs through the blood brain barrier and into the brain. This same Peer-Reviewed and Published document now provides proof that Polysorbate 80 in vaccines that is used to keep ingredients from clumping, may be capable of delivering highly inflammatory vaccine ingredients, including mercury and aluminum, into the brain and CNS of infants, children, and adults, hyper-sensitize immune cells in the lining of the gut and airways so as to cause or enhance food and environmental allergies and asthma, disrupt methylation, transsulfuration, and hormone production, and cause encephalitis, gut inflammation, and malabsorption; all of which we have observed in our study group of over 100 families, and all of which are associated with Autism and Autoimmune Disease. Polysorbate-80 coated vaccine nanoparticles may have contributed to the intracranial hypertension and a Lumbar Puncture Opening Pressure of 35 in one teen.

TESTING / COMMON MARKERS  

We found that 25 Hydroxy vitamin D [25(OH)D], Quest Diagnostics Test Code 17306, was always below lab-normal in all who were tested, typically ranging from 7 to 25 ng/ml. We observed that intracellular magnesium was universally low, even though serum magnesium was typically low, but within range.  We observed that many of the more seriously affected presented with symptoms of a Thiamine deficiency, even though thiamine tests were within range.  We found that an LPS Stimulated Comprehensive Cytokine Panel results typically showed relatively normal base counts, but two or more of the LPS Stimulated Cytokine counts were typically less than half of their acceptable lab value. We also discovered that test results from an NK-CD57 test: LabCorp Test Name: HNK1; LabCorp # 505026, will typically uncover below lab-normal counts ranging between 8 and 50 in girls. Minimum LabCorp acceptable count is 63 or greater. We observed similar symptoms which varied mainly in severity. Upon testing, we found that the same similar set of pathogens were typically involved. Results of Pathogen testing will be given on request.

ABSTRACT - Older with more discussion, with additional references (Abstract will be shortened to 300 words, and References will be removed when published.)

Recombinant vaccines, such as HepB, MMR, and the Gardasil HPV vaccine, use an exceptionally strong, broad spectrum adjuvant that is designed to aggressively stimulate the immune system. At the request of the media, we investigated reports of debilitating symptoms and death following administration of the Gardasil HPV vaccine. We observed that these children and adults were almost always asymptomatic prior to vaccination. We observed that those who were most active and athletic prior to vaccination, appeared to suffer the quickest onset and most severe group of virtually identical debilitating symptoms following vaccination. The average person in this group was typically misdiagnosed by 10 or more doctors over a period of up to eight years, and reported multiple emergency department visits at two or more hospitals or clinics, and was ultimately diagnosed with multiple infections, including CDC Positive for Lyme Disease. We confirm the findings of RAMON et al (1925-26) who documented that the presence of infection(s) in a host being vaccinated can elicit a stronger and unpredictable immune response (1). We observed this phenomena and found that the majority of children and adults in our study of over 100 families, tested positive for the Human Leukocyte Antigen haplotype, which is associated with infectious diseases and a high pathogen load (2).  We further observed that formerly exotic infectious disease pathogens that were formerly associated with a foreign geographic region, have migrated globally, such as the discovery of Bartonella DNA  in 95% of fleas from Norway rats that were trapped in Los Angeles California (3). Bartonella species is a member of the Alpha 2 subgroup of Proteobacteria, and has even been found in kangaroos in Australia. Bartonella is strongly associated with Lyme Disease. I was told as recently as 2012 by the Infectious Disease Specialist at the Broward County Florida Health Department, that Bartonella was only found in Peru. Recent estimates indicate that up to 51% of domestic and ferrule cats in the United States are infected with Bartonella, that can be passed on to humans, and the CDC has finally acknowledged that there are 300,000 new cases of debilitating Lyme Disease each year (4), but subsequent research Papers put this figure at or close to 1,000,000 new cases each year, most all of which remain undiagnosed.

Polysorbate-80 is a Surfactant that is added to the Gardasil HPV vaccine to form a coating around the vaccine ingredients to stop them from clumping together. We observed that this coating appears to change the HPV16-L1 protein particles that are bound to an aluminum nano-particle substrate (adjuvant), into what appears to be a "Bullet Protein." This Polysorbate-80 coating also appears to help allow the aluminum-bound antigen to maintain its original nano-particle form, and may help prevent it from separating from the antigen or changing into a larger aggregate. This coating also appears to allow the vaccine to pass through the blood brain barrier and gain access to the brain and possibly other organs in the body, such as the spleen, which was found by noted geneticist, Dr. Sin Hang Lee, to contain HPV16-L1 protein fragments in autopsy tissue, six months after injection. We found the most common result of this enhanced immune response in the presence of infection(s) was a hyper-sensitization of immune cells in the epithelial lining of tissue in airways and in the gut, which resulted in new and/or enhanced food and environmental allergies plus a Histamine Intolerance. We also observed the activation and virulence of multiple dormant pathogens which appeared after the initial sepsis-like reaction to the vaccine ingredients (5).

Severe reactions to the administration of the Gardasil HPV vaccine, especially in those sensitive to dust, mold, or fungus appears to trigger eosinophils to quickly dump histamine into the blood, which, together with a non-allergic Polysorbate-80 reaction that produces nitric oxide, may result in severely dilated blood vessels and a sudden drop in blood pressure, which may result in dizziness and/or a loss of consciousness in some individuals immediately following the HPV vaccination. Blood pressure dropped to 50/32 in one patient, who is now a doctor. Hypotension was typically followed by the development of a Histamine Intolerance (HI) which may result in elevated histamine production by mast cells, which may result in dilated blood vessels, which may typically result in Hypotension and Postural Orthostatic Tachycardia Syndrome (POTS), with symptoms of lightheadedness and a fast pounding heart upon standing. Sustained gut inflammation may lead to Gastroparesis if left untreated. We observed that these and other debilitating conditions were found to be most severe in formerly active people who carry the HLA-DR15 genetic mutation and who may also carry the genetic mutation that causes Ehlers-Danlos Syndrome Type-3, along with a genetic mutation which affects transsulfuration, especially the CBS-699t allele, which results in a deficiency of Cystathionine Beta-Synthase. A significant number tested positive for the MTHFR mutation. These people are commonly of Northern or Western European ancestry, and many reported Native American Ancestors, including, but not limited to Cherokee Nation, Hopi, Lakota, and other Native American Tribes.

Most in our study showed signs of Hypermobility (Ehlers-Danlos Syndrome, Type 3), while others were Atypical for Hypermobility, but had siblings or other family members who presented with Hypermobility (are double jointed).  Very few reported allergies, asthma, acne, and eczema, prior to the Gardasil injection, however most of the deaths in this study involved a history of asthma or relatively recent respiratory infection. Many who had no previous history of eczema presented with eczema after Gardasil. Some common symptoms after the Gardasil injection include, but are not limited to: Mood Swings; Insomnia; short term memory loss; Hypotension; POTS; Intracranial Hypertension with LP opening pressure around 35; severe 25 Hydroxy Vitamin D deficiency which may ultimately result in Hashimoto's and Interstitial Cystitis; low intracellular magnesium; failure of methylation cycles and hormone production; Idiopathic Thrombocytopenia Purpura; impaired thiamine uptake; and much more following the Gardasil HPV vaccination. We also observed that a significant number developed delayed onset seizures, ranging from months to years.

We reviewed a sample of recent, well-documented abstracts and literature on the use of Polysorbate-80 as a drug delivery vehicle, capable of delivering payloads into the cytoplasm of individual cells and breaching the blood brain barrier to deliver drugs to the brain and Central Nervous System (6)(7)(8)(9). We now view the use of Polysorbate-80 coated vaccine antigens and adjuvants as a potentially dangerous threat to human life. Our own 5 year study revealed that the prolonged inflammation caused by the Gardasil HPV vaccine and its Aluminum Hydroxyphosphate Sulfate adjuvant was notorious for initiating cascades of debilitating events by awakening dormant pathogens, including, but not limited to, those pathogens related to tick-borne illnesses, such as Borrelia burgdorferi (Lyme Disease), plus related co-infections such as Bartonella, Babesia, Mycoplasma, plus enteroviruses, and more.

 

(1) "Vaccine adjuvants: Current state and future trends,"   doi:10.1111/j.0818-9641.2004.01272.x
.... http://www.nature.com/icb/journal/v82/n5/full/icb200475a.html
(2) "HLA and Infectious Disease"
....
http://cmr.asm.org/content/22/2/370.full
(3) "
Molecular detection and identification of Bartonella species in Xenopsylla cheopis fleas collected in Norway rats in Los Angeles, California"
....
http://www.ncbi.nlm.nih.gov/pubmed/21908631
(4) "Severity of Chronic Lyme Disease compared to other chronic conditions: a quality of life survey"
....
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976119/
(5) "Reactivation of Multiple Viruses in Patients with Sepsis"
....
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0098819
(6) "Specific role of polysorbate 80 coating on the targeting of nanoparticles to the brain"
.... http://www.ncbi.nlm.nih.gov/pubmed/14967540 
7) Intracellular drug delivery using polysorbate 80-modified poly(D,L-lactide-co-glycolide) nanospheres to glioblastoma cells.
.... http://www.ncbi.nlm.nih.gov/pubmed/21171814
(8) Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles
.... http://www.ncbi.nlm.nih.gov/pubmed/12669961
(9) Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease
....
http://www.ncbi.nlm.nih.gov/pubmed/18291351

 

 

 


EXPANDED ABSTRACT (This version is intended as a core group pre-release, and contains info and comments that may not be present when published)

We observed that sustained inflammation, especially the inflammation resulting from the extremely potent aluminum adjuvants required for today's recombinant vaccines (HepB, MMR, Gardasil HPV, etc.), together with people who may carry most, but not necessarily all of the following (genetic) conditions:

1)
the Human Leukocyte Antigen genetic mutation (HLA Haplotype, commonly the HLA-DR15 genetic mutation) associated with a higher active and dormant pathogen load in people of Northern and Western European ancestry 
2)
the Ehlers-Danlos Type 3 genetic mutation (associated with Hypermobility, but may be asymptomatic, while a parent or sibling may be symptomatic),
3) a family history of Glandular Fever (Mononucleosis) or
4) severe food allergies, or
5) severe pulmonary disorders, including, but not limited to asthma and pneumonia,
6)
a Glutathione S-Transferase deficiency, (typically GSTM1 or GSTP1)
7) a Cystathionine Beta-Synthase (Transsulfuration) deficiency (CBS-699t genetic mutation)....
.... may produce enhanced, prolonged, sustained, or even uncontrolled inflammation (cytokine storm) in response to a vaccination. This abnormal inflammatory immune reaction may then signal pathogens, including dormant pathogens, to become virulent.  We observed that some of the most common pathogens found in these iatrogenic children and adults are related to pathogens usually found or associated with Lyme disease and (biting) insect-borne infectious diseases.

We observed and confirmed the Peer Reviewed and Published findings of Ramon et al, 1925-26, that vaccinating a host with an infection produces an enhanced and unpredictably strong immune reaction, which we observed can produce:

1). Hyper-stimulation of immune cells in the lining of the GI Tract, resulting in new or enhanced food allergies, which may then result in:
2). Histamine Intolerance, which may cause:
-a). Postural Orthostatic Tachycardia Syndrome;
-b). Irritable Bowel Syndrome;
-c). Gastroparesis (if left untreated)
3). Self-Sustaining Inflammation.

If the allergic foods *plus* all moderate to high histamine-containing foods are not removed from the diet, the result can be mild to critical gut disruption resulting in malabsorption; nutrient, enzyme, and hormone deficiencies plus anomalies which may then result in eczema, urticaria, hives, and further cascades of debilitating events including, but not limited to death and paralysis. We have found these symptoms to be mostly "epigenetic," that is, once triggered, the genetic expression or modified behavior of that cell does not instantly return to normal if the trigger is suddenly removed, but, at least in the case of over-stimulated histamine-producing mast cells, remains in a hyper-activated state for an extended period, thus requiring a dietary and/or other lifestyle change.

Author's Note: It interesting to note that Dr. Paul Offit's RotaTeq vaccine also disrupted the gut, resulting in Intussusception and death in some children. We believe that the GI Tract is an overlooked, but critically important factor in the vaccination process.

We observed and confirmed that the elevated level of inflammatory cytokines, expressed during sustained inflammation, may act as incubators for active and dormant pathogens. These infected leukocytes then appear to migrate and spread the infection, especially to joints, which become inflamed and painful.

We observed that the Gardasil HPV vaccine is notorious for awakening dormant pathogens and enteroviruses, especially pathogens carried by ticks and other biting insects. Most members of the group had no noticeable symptoms of any pathogen prior to receiving their vaccination.

We observed that genetic mutations that had produced no symptoms in the past, appeared to be suddenly "switched on." As an example:

1) Formerly active and asymptomatic children who carried the HLA-B27 genetic mutation were suddenly being diagnosed with Ankylosing Spondylitis.
2) Formerly active and asymptomatic children who carried the CBS-699t allele were now being diagnosed with loose joints, connective tissue disorders, and low Glutathione.

We observed the failure of virtually all pediatricians and many well-known hospitals to recognize symptoms of insect-borne infectious diseases in members of our study group, even though the CDC has warned of 300,000 new cases of Lyme Disease each year. Hannah R. and Cailen Mc. were both recently diagnosed CDC Positive for Borrelia burgdorferi (Lyme Disease) around November of 2014.

We observed that the majority of members in the study group developed urticaria and eczema after their vaccination, and a lesser number developed Immune Thrombocytopenia Purpura (ITP). Most stated that they had never had eczema prior to receiving the HPV vaccine, and no one reported a previous case of ITP. A significant number of females also developed Interstitial Cystitis, with a significant number of cases occurring one or two years after their first HPV vaccination.

We observed an unwillingness by doctors to cooperate, bordering on hostility, if a parent suggested that the vaccine may have caused their child's illness:

I). 13 yr old Selby P. was reportedly an active child, who rarely if ever got sick. Selby did have a medical history of IBS, which was diagnosed at age 8. Selby was of Irish and other European descent, and also had native American (Cherokee) ancestors. Selby had all three Gardasil shots. In addition to newly acquired seizures, hair loss, fatigue, head and joint pain, poor memory, insomnia, and lack of muscle tone, resulting in scoliosis, surgeons at Children's Hospital in Atlanta Georgia, removed her gallbladder and her appendix in an effort to relieve her abdominal pain. Selby had been diagnosed with IBS at age 8, but was given the Gardasil HPV vaccine anyway.

II). 18 yr old male, Zack O, was a runner on his high school track team. He was looked up to as the one to beat in a two mile run. Zack and his mom have the same Kaiser Permanente Primary Care Physician (PCP), Dr. Hamesh Patel. Zack's mom was diagnosed with Tumid Lupus, an autoimmune disease. Her son, Zack, was vaccinated anyway with the Gardasil HPV vaccine, despite the family history of autoimmune disease, which Doctors of the Columbia Medical Association are now warning about. After one shot of Gardasil and 16 months later, 6 foot Zack now weighs 106 pounds and walks with a cane. Zack has been under the care of doctors at California's Kaiser Permanente, who appear to have negligently failed to check Zack's vitamin D level for a year. They only did so because of the repetitive insistence of Zack's mom, in order to help her suffering son. Zack has now been diagnosed with a fractured L5 Vertebrae (consistent with iatrogenic Osteomalacia), which is consistent with acutely low 25(OH)vit-D. Zack's vitamin 25(OH)vitamin-D was allowed to plummet to 16 ng/ml by medical professionals by doctors at Kaiser Permanente, who told him he "needed to exercise." Zack suffers from the same symptoms reported by numerous Gardasil HPV vaccine victims around the world. It should also be noted that Kaiser Permanente's head of Infectious Disease is Dr. Arnold Matthew Henson, MD, and that oter patiens of Kaiser anecdotally report similar mistreatment with Lyme Disease. Kaiser is also part of the "VACCINE SAFETY DATALINK" to prove that vaccines are safe, and receives funding from the CDC/HHS. HHS owns patent rights to Gardasil. Kaiser Permanente is also the entity that vaccinated Zack, telling the family that the Gardasil HPV vaccine is safe.

 

. As a side note, Researchers are now warning of the discovery of Borrelia Miyamotoi, a heretofore unknown form of spirochete with symptoms reported to be more severe than Lyme Disease. The research Abstract for Borrelia Miyamotoi was publish in mid 2015. Zack has the prerequisites of this syndrome, including Native American Ancestors. Kaiser Permanente  Rheumatologist Dr. Ricardo Bardales refuses to run tests that other doctors have used to help uncover hidden conditions in these kids.

1). In one of many cases in our study group of approximately 100 children and adults suffering adverse reactions following their Gardasil HPV vaccination, Oklahoma Children's Hospital REFUSED to test Theresa R's daughter, Hannah, for Lyme Disease, even though Theresa R. had recognized symptoms of Borrelia burgdorferi (Lyme Disease) in her daughter. Hannah was misdiagnosed by the Oklahoma Children's Hospital, and her health continued to decline. Hannah suffered many unnecessary debilitating symptoms, including seizures, until she was recently tested for Lyme by a competent Medical Doctor. Hannah's test results came back "CDC Positive" for Lyme Disease (Borrelia  burgdorferi). Hannah is finally being treated by multiple specialists in an attempt to mitigate the damage from untreated CHRONIC LYME, due to Oklahoma Children's Hospital.

2). In June of 2014, in a virtually identical case, a female Rheumatologist in Georgia at the Atlanta Children's Hospital REFUSED Tabitha M's request to have her daughter Cailen tested for Lyme. Cailen was later tested by a competent Medical Doctor and was also found to be CDC Positive for Lyme Disease. Rheumatologists in the United States recently saw a 15% surge in their income, and in at least one case, Cailen's, the cause was Lyme Disease, which makes us question how many other Rheumatologists are unwilling to cure their patients by finding the CAUSE of their patient's pain, instead of merely treating $ymptom$.

3). In another case, a doctor at a Dublin Georgia hospital apparently did not know how to interpret LabCorp HNK1 (NK-CD57) test results which uncovered a critically low NK-CD57 COUNT of "8". Megan F. had been admitted for seizures. The doctor and the hospital released 15 yr old Megan F. with no follow-up and no diagnosis.

4). Haleigh B. was seen by Fort Collins Youth Clinic since she was born in January of 1997, and except for being given medication for seasonal allergies and an allergy to cats, her mother reports that she was in good health. On or about June 26, 2008, 10 yr old Haleigh B. was given her first dose of the Gardasil HPV vaccine, together with the FluMist Flu vaccine, which according to RAMON et. al., 1925-26, would have unpredictably increased Haleigh's immune response. Fort Collins Youth Clinic falsely reported that Haleigh had no allergies, even though they had prescribed medication for her allergies months before. Haleigh followed the typical onset of debilitating adverse reaction symptoms, which included fatigue, severe headache, stomach pains, chest pains (mom described symptoms consistent with of pleurisy), and nausea. When Haleigh complained of stomach pains, doctors at Medical Center Of The Rockies removed Haleigh's Gallbladder. Six months later, Children's Hospital Of Denver removed Haleigh's appendix when she complained again of stomach pains. The operations reportedly made Haleigh feel worse. Around February of 2014, Haleigh was diagnosed as having West Nile antibodies. The comment from her pediatrician was "Everybody has West Nile." Around May of 2014, with Haleigh in the room, Dr. John Taliaferro of Loveland Colorado, told Tamara B that her daughter Haleigh had CONVERSION DISORDER (It's all in her head). When the mother asked if Haleigh just imagined that her Gallbladder stopped working, Dr. John Taliaferro cynically responded: "That was the start of it." Tamara B, asked Dr John Taliaferro if it could have been the Gardasil HPV vaccine, and the doctor appeared to look at something on his computer screen. Dr John Taliaferro then told the mother and daughter that there were no reports of any bad reactions.  Since the mother and daughter both new that almost 200 deaths and 40,000 adverse reaction reports had been filed with the United State Government's VAERS reporting system, they both new that Dr. Taliaferro was lying. Tamara B had done everything these doctors wanted, from allowing them to remove possibly good organs from her daughter, to faithfully bringing her daughter in for her second Gardasil shot, all to prevent being charged with negligence by these doctors. Tamara B and Haleigh B now caught Dr. John Taliaferro in a lie. Haleigh B has been sick for six years, and this doctor is now trying to blame the mother and the daughter for HIS mistakes and incompetence to properly diagnose Haleigh's IATROGENIC condition. Haleigh continues to be sick, and acquire new illnesses. On May 6th, 2014, MCkee Medical Clinic diagnosed Haleigh B with Mononucleosis. Haleigh, who had hardly, if ever, missed a day of school, has missed 97 days after getting her Gardasil HPV vaccination. Haleigh is on Medicaid, and it appears doctors are draining her account doing "procedures," none of which are improving Haleigh's quality of life. Because the family does not have the thousands of dollars needed for special medical testing, Haleigh remains sick as of February 2015.

5). In still another case, I was contacted by the mother of a 24 yr old female who was an "A" student prior to receiving the Gardasil HPV vaccine when she was 17 yrs old. This formerly "A" student now found it difficult to study and has to be carefully watched while going to the bathroom to prevent her from rubbing feces on the bathroom wall. On one occasion, her mother reported that she caught her 24 yr old daughter drinking water out of the toilet bowl through a straw, where she had dumped her meds. She was running fevers and having extended menses on a 10 to 14 day cycle, which is consistent with such things as Chronic Epstein Barr (CAEBV). After her mother took her to a competent physician several hours away, she was formally diagnosed with CAEBV.

6). Our interview with Doctor Lona C. made us aware that girls were not simply fainting after receiving the Gardasil HPV vaccine; they appeared to be going into a type of septic shock resulting in a massive histamine release, in addition to the release of vasodilating nitric oxide, which is released in a non-allergic chemical reaction as a result of the Polysorbate-80 used as a surfactant in the Gardasil vaccine. The histamine release then caused blood vessels to dilate, resulting in dangerously low blood pressure. Dr. Lona C. was in medical school when she received the Gardasil HPV vaccine. She returned to class minutes after her vaccination, and lost consciousness. Her vitals were taken. Lona's blood pressure had dropped to 50/32. This is not simply fainting. This condition occurred well AFTER the vaccine was administered, and had similar symptoms to septic shock.  Dr. Lona C. and many others typically went on to develop a Histamine Intolerance. We believe that this histamine condition is the cause of Postural Orthostatic Tachycardia Syndrome. The histamine release becomes sustained because most people in our study group developed a new Histamine Intolerance, which makes it mandatory to remove moderate and high-release histamine foods from the diet. We further believe that this condition resulted in the death of 12 yr old Meredith Prohaska, four hours after her Gardasil HPV vaccination.

7). Alicia K, a healthy and active pharmacist technician received the Gardasil HPV vaccine one week before her 21st birthday in December of 2006. Her symptoms of fatigue, dizziness, and chest pain became so bad that she was transported to the hospital one month after her first HPV vaccination. After her second Gardasil HPV vaccination, Alicia developed a severe case of Postural Orthostatic Tachycardia Syndrome (POTS), frequent fainting spells, and a heart arrhythmia. In August of 2007, after her fainting episodes had resulted concussions, facial bruising, and shoulder injuries, her cardiologist implanted a pacemaker. In the seven years since, Alicia is unable to maintain a full time job, had two complicated pregnancies, and was forced to abandon future job goals.

8). Madison S. is a young lady who turned 14 yrs on February 9. Madison has a 17 yr old brother. Madison's family history includes a mom with a dx of Lyme and Mononucleosis, with genetic markers for CMT and EDS-3 (hypermobility). Madison has a personal medical history which includes allergies and asthma, and has had a standing prescription for Albuterol from her pediatrician. Madison has has been prescribed Albuterol since about 2008. Allergies and asthma are contraindications for the Gardasil qHPV vaccine per the vaccine insert.  She also has red flags - genetic indicators consistent with Ehlers-Danlos Syndrome. 

Madison received the Gardasil HPV vaccine Jan 24 2013, by Dr Suzanne R. Peplinski DO, even though there was a warning about allergies to yeast (mold/dust) sent to doctors along with the vaccine. The doctor was aware of her asthma, and had reportedly prescribed Madison's Albuterol. Madison's mother was told that the Gardasil HPV vaccine was safe. According to Madison's mom, Madison had recently been found to be positive for allergies to dust/mold. MERCK warns not to give this vaccine to anyone allergic to mold. Madison later suffered multiple organ failure (4-27-13), TACHYCARDIA, and (temporary) blindness in her left eye, bleeding out vaginally, orally, rectally, ears, etc... her mom says even she didn't loose as much blood during delivery, and that Madison's hospital room resembled a murder scene. 

On January 22 2014, Madison's school counselor, Jennifer Burdick, interrogated 13 yr old Madison about medical procedures she had while at the hospital. Jennifer then reported Madison's mom to Child Protective Services because she felt vaccines couldn't injure a child, so the mother must have done it.

Prior to Gardasil, Madison enjoyed Cheerleading and Dancing, but pain now makes it impossible. Madison was admitted and treated at Children's hosp of Detroit and other hospitals for slurred and incoherent speech, lethargy, liver failure, dehydration, 105.2 temp, tachycardia, shading on lower left lobe of lung, and multiple organ failure. She also suffered from a honeycomb rash (Livedo Reticularis),  projectile vomiting, 5.9 bilirubin which became elevated in 16 hrs, liver doubled in size, pneumonia, and more.

9). "J" is a 24 yr old female who received 3 doses of the Gardasil HPV vaccine when she was about 16 yrs old. "J" reports a medical history of Mononucleosis at age 12, and a diagnosis of Lyme Disease (Borrelia Burgdorferi) at age 13. Lyme Disease and co-infections associated with Lyme are found in almost every girl tested. We have found that a history of Mononucleosis is virtually a 100% predictor for a life threatening reaction to the Gardasil HPV vaccine. "J" is one of the cases that confirms our findings that the Gardasil HPV vaccine appears to be capable of awaking dormant pathogens, including Lyme. "J" has suffered from adverse reactions from MERCK's Gardasil HPV vaccine for the past 7 years, and her grandfather was killed by VIOXX, another defective MERCK product that caused an estimated 180,000 heart attack, for which 27,000 families sued MERCK in a court of law, and MERCK lost. Merck, the company that reportedly caused an estimated 180,000 thousand heart attacks in adults, now brings you the Gardasil HPV vaccine for your child.

10). We observed that approximately 50% of our study group of more than 100 had a significant exposure to an area that was normally sealed or off limits to regular human traffic, such as a wooded area or (part of) a building that had been kept sealed.

a). Brittney F. is a teen whose church group volunteered to help renovate intercity homes belonging to the elderly. Brittney went through a crawl-space under the residence, crawling through an area occupied by rodents, spiders and other similar creatures. Brittney became ill. During a trip to her pediatrician to remove a cyst on her leg (a red flag symptom of Bartonella) her pediatrician talked her into receiving the Gardasil HPV vaccine, and Brittney began to experience severe adverse reactions, including seizures, and had to drop out of school.    

b). "Pooker" is the nickname of an 11 year old Canadian girl who moved into a vacant house with her mother. The house had been uninhabited for two years. The previous owner had kept two dogs in the basement, and piles of dog and rodent feces, mold, dirt, and other debris littered the basement floor. "Pooker" came downstairs where her mother was sweeping up this toxic waste, and breathed in this deadly cloud. Both her and her mother became ill. "Pooker" received the Gardasil HPV vaccine several months later, without parental consent, and has experienced debilitating new symptoms which include asthma, severe fatigue, gait disturbances, digestive issues, POTS, memory loss, seizures, and other symptoms.

c). Carlie W. spent a summer working in a Cloister in Pennsylvania that was used as a tourist attraction. The building was only opened on the weekend, and was uninhabited the rest of the time. Carlie, unlike the previous two cases, showed no signs of illness prior to receiving the Gardasil HPV vaccine.

Carlie W and other girls in our study were seen by specialists at Children's Hospital Of Pennsylvania (CHOP) and were also misdiagnosed. Carlie, like the MAJORITY of HPV vaccine-injured children, was wrongfully misdiagnosed with "CONVERSION DISORDER". Without a competent diagnosis and treatment plan from Children's Hospital Of Pennsylvania, Carlie W became home-bound, suffering many needless seizures. Carlie's seizures stopped upon treatment for Lyme disease.

 

We observed that Dr. Paul A. Offit, MD, is listed as Chief of Infectious Diseases and director of the Vaccine Education Center at The Children's Hospital of Philadelphia (CHOP). We observed that Dr Paul Offit has written and published that vaccines are safe, and one of his statements appears on the Children's Hospital Of Philadelphia website. Paul Offit claims that an infant can safely receive 10,000 or even 100,000 vaccinations. When I researched Paul Offit's scientific reference for this outrageous claim, I found that his reference is "THEORETICAL IMMUNOLOGIST" Professor Melvin Cohn, who teaches at the Salk Institute. One of Melvin's sayings is on his faculty page is: "While other immunologists use Petri Dishes, I use my brain." Many people who trusted Offit's writings might be unsettled to learn that Paul Offit bases vaccine safety for multiple vaccines on Professor Melvin Cohn, a THEORETICAL IMMUNOLOGIST, who based his "Laws" on how he thinks a THEORETICALLY perfect immune system, in a THEORETICALLY perfect body, in a THEORETICALLY perfect environment, that eats a THEORETICALLY perfect diet, and gets a THEORETICALLY perfect amount of sleep, should react to a THEORETICALLY PERFECT VACCINE. Unfortunately we live in the REAL WORLD where a THEORETICALLY perfect ship called the TITANIC sank on her maiden voyage when it met a REAL WORD iceberg. Humans are not perfect, and many people have genetic mutations and thousands of different infectious pathogens when vaccinated, so no two immune system are going to respond exactly the same. As an example of genetic mutations can modify how the body works, many women have died of breast cancer because their oncologist didn't bother to check if they had a gene mutation in the CYP450 Pathway that would prevent anti-cancer drugs, such as TOMOXIFEN from being properly metabolized. In cases like these, doctors bury their mistakes. The idea of putting 100,000 0.5 milliliter doses of any vaccine into an infant is absurd, because you cannot separate an adjuvant or other ingredient from a vaccine, and still call it a vaccine. Dr Paul Offit would be putting about 13 U.S. Gallons (50 Liters) of vaccine into an infant, which would immediately kill the child. (I strongly recommend that Dr. Paul Offit be placed in a Psych ward and properly medicated until his illusions of grandeur subside -or- publicly demonstrate his hypothesis by injecting himself with 100,000 doses of the Gardasil HPV vaccine. Regarding Dr. Paul Offit's comments on vitamins, minerals, and other supplements, these are what allow many people with genetically compromised methylation cycles, etc., to thrive, and since a reported 70% of Americans are deficient in magnesium alone, which is a factor or co-factor in about 300 different chemicals that the body makes daily, Dr. Paul Offit, along with the Children's Hospital Of Philadelphia would profit financially if people could not achieve proper nutrition through supplementation, and become ill. As an example, many heart attack victims are given medication that inhibits the production of CoQ10, which must be supplemented for proper health. In summation: Dr Paul Offit is a QUACK, and the Children's Hospital Of Philadelphia, whose medical practitioners have failed on multiple occasions to diagnose a few of the 300,000 cases of Lyme Disease that the CDC warned about, may not be the best hospital to take a sick child.

Other people, such as Sen. John McCain, have also tried to ban or bring supplements under FDA control, but if you follow the money, during his 2008 presidential election filing disclosure, the McCain family revealed that it owns $25,000,000.00 worth of stock in Gilead Sciences, the company that makes TAMIFLU. In still another blatant attempt to extort money from the American Public and keep them sick, pharmaceutical companies, together with the FDA and CDC engaged in a lucrative scheme which involved extorting typically $100.00 to $200.00 each month for antacids that allowed the H-Pylori bacteria to thrive in Americans with Peptic Ulcers, instead of giving them 7 days worth of antibiotics that would have cured them. Despite the many deaths, debilitating pain, and much more, not one doctor, pharmacist, or drug company was ever prosecuted for this scam.

** We observed that there appears to be a number of discrepancies between how the Aluminum adjuvant in the HPV vaccine is THEORETICALLY suppose to work, and how it actually works in the REAL WORLD. Medical school teaches us that the vaccine adjuvant separates from the antigen (L1 Proteins) typically within 24 hours, but autopsy tissue from two deceased teenage girls from different families revealed that the L1 Protein fragments from the Gardasil HPV vaccine were still firmly attached to the aluminum nano-particle substrate from the vaccine. This implies that the aluminum did not form a larger aggregate structure upon injection into the body, but apparently held together with the antigen, and may actually been a form of Polysorbate-80 surfactant "bullet protein" which was easily distributed throughout the body. Polysorbate-80 has been confirmed to be a good delivery mechanism to deliver drugs not only through the blood brain barrier, but also into the cytoplasm of a cell (intracellular drug delivery). We have been seeking answers by contacting Chris E. and others working with vaccines and aluminum nano-particles, and they are currently working on an answer.

We observed that "CONVERSION DISORDER" appears to be a universal, almost pre-planned diagnosis for the majority of children presenting with an adverse reaction to the HPV vaccine. This is especially true in the case of Carlie W and other girls who were patients at CHOP.

We observed the following occurred with varying degrees of severity in most, but not necessarily all members in this study group, listed in approximate order of occurrence: fatigue; difficulty breathing, including asthma; lightheadedness; irritability; debilitating and excruciating "head pressure" in the majority of subjects which may last for days, weeks, months, or years; depleted levels of 25 Hydroxy Vitamin D (<30); low or depleted INTRACELLULAR magnesium (serum magnesium typically remained at the low end of lab-normal); joint pain; mood swings; Aphasia; inability to concentrate, typically described as "brain fog; seizures (ranging from TIA to Grand-Mal), including seizure activity that started two years after vaccination in several children; muscle spasms, tremors, jerky movements in arms and legs (some girls reported feeling a "phantom tremor" when their limbs were not moving); inability to walk properly (disturbed gait); weakness, including difficulty in picking up food containers, pots, plates cups, etc. (Note: nerve conduction tests were typically within lab-normal); blurred vision; skin that is painful and sensitive to the touch, including discomfort from tight-fitting clothes, and painful skin while reclining; hallucinations; and a heightened sensitivity to light (photophobia) and sound. A few members of this study group were checked for Schizophrenia. Most eventually complained of heart pain and an inability to take in enough oxygen even though their lungs were clear (a minority of these were diagnosed with Babesia, which can "eat" the oxygen-carrying iron atom out of a red blood cell. Insomnia was virtually universal, probably due to elevated levels of cortisol inhibiting the production of melatonin by the pineal gland. We believe the genesis of these adverse reactions may be result from an acute allergic reaction to the mycotoxins and other (DNA) contaminants contained in the vaccine. These vaccine contaminants are acknowledged by the FDA after they were found in 10 vials of HPV vaccine that were distributed and tested in France, together with the findings of noted geneticist Dr. Sin Hang Lee, who uncovered this in tissue from two deceased teenage girls at autopsy. These vaccine "allergy" reactions may typically cause a quick release of histamine from eosinophils, and a slower release by mast cells which may cause sudden death in people with a history of Long-QT, asthma, pneumonia, or similar upper respiratory condition, due to the sudden dilation of blood vessels by histamine, together with a type of "histamine foam" possibly caused by a "cytokine storm" produced in the lungs and airways, as observed at autopsy in the case of 17 yr old deceased teen, Jessica E. In another recent death, 12 yr old Meredith Prohaska, a diagnosed asthmatic who was highly allergic to mold, died within four hours of receiving her Gardasil HPV vaccination. Her pediatrician was aware of her asthma and mold sensitivity, but still administered the Gardasil HPV vaccine, which appears to be contrary to the package insert.

We observed that Low Dose Naltrexone (LDN) helped reduce pain and nausea and allowed members to eat more foods without experiencing aabdominal. LDN appears to help by binding opioid receptors, thus apparently triggering the release of endorphins and enkephalins. Parents have also commented that LDN helped with insomnia, improved mood, and allowed their child to sleep about five continuous hours before waking, instead of the typical two hours of sleep they were getting.

We observed that sudden vaccine-associated deaths may occur on a timelines ranging from a matter of hours after a vaccination, to a matter of weeks. We believe that a window of several weeks appears to exist in which the adverse response to the vaccine is primarily an "allergic response", after which this response may combine with an antibody response produced by the immune system. We believe that the initial "allergy based response" poses the greatest risk for sudden death because it may produce a cytokine storm which may result in a "histamine foam" may coat the lungs and airways, and prevent re-oxygenation of blood.

We observed that a significant number of "loss of consciousness" events and deaths occurred during or after bathing, and hypothesize that Orthostatic Intolerance (POTS) with or without lowered blood volume may have contributed to or caused the sometimes fatal event. We hypothesize loss of consciousness may have occurred when hot water in the shower or tub may have suddenly dilated blood vessels in extremities, thus further lowering the already low blood pressure associated with Postural Orthostatic Tachycardia Syndrome. We strongly urge that a warning be issued to all families suffering from POTS to avoid hot baths and showers, and to have someone present (other than her teenage boyfriend) while a girl is bathing.

This histamine release may also be extremely dangerous to the (developing) brain because elevated histamine may cause a permeation of the blood brain barrier, thus allowing inflammatory vaccine components, including the potent aluminum adjuvants found in recombinant vaccines such as HepB, MMR, and and the HPV vaccine to enter the brain. This may not only damage (developing) critical cognitive and motor skill structures within the brain, but may also cause antibodies to be produced within the brain. This may contribute or be the cause of autism in infants and toddlers. This cascade of events may now initiate inflammation within macrophagic glial cells inside the brain. When glial cells become inflamed, nearby Oligodendrocytes may be inhibited from producing myelin for the sheath that surrounds nerves. This is how demyelinating disorders may actually begin, including Multiple Sclerosis.

We observed a hyper-activation of immune cells in the GI Tract which resulted in:
 
a) new or enhanced food allergies;
b) Histamine Intolerance;
c) malabsorption;
d) failures of multiple metabolic cycles, pathways,
enzymes, and hormones, especially in the presence of genetic mutations associated with a deficiency of Glutathione S-Transferase (such as the GSTM1 polymorphism), and Transsulfuration (such as the CBS-699t genetic mutation);
e) Irritable Bowel Syndrome, which may result in
f) Gastroparesis if not treated.

The resulting Oxidative Stress:

1) caused the body to excrete Magnesium, resulting in the depletion of intracellular magnesium, even though serum magnesium remained within gate;
2) resulted in a serum deficiency of 25 hydroxy Vitamin D;

3) inhibited the uptake of Thiamine, resulting in an intracellular Thiamine deficiency;

These deficiencies may then result in cascades of varying degrees of debilitating or life-threatening symptoms and autoimmune disorders, which, in some cases, may ultimately result in death.

November 5, 2014: Our research has uncovered something very unexpected. Many of the most seriously ill children and adults have an ancestor belonging to the Cherokee Nation (Native American Indian).

SUMMARY: Vaccination can be an unpredictable medical procedure in which the immune system is over-stimulated to produce antibodies to an antigen in the vaccine. However, a vaccination may produce an uncontrolled and unpredictably dangerous immune reaction in the presence of certain pathogens, especially tick-borne pathogens associated with biting insect vectors.

 

Notes on Unexpected or Sudden Death After the HPV Vaccinatiotrong>n:

Meredith Prohaska was happy, and healthy 12 yr old Wisconsin pre-teen who loved bsketball. Meredith Prohaska died 4 hours after receiving an injection of the Gardasil HPV vaccine. Meredith Prohaska's death appears to have been completely avoidable, if her pediatrician had been less greedy and read the warning on the Gardasil vaccine package insert. The CDC says that caregivers need to be informed of possible adverse vaccine effects, and that the administration of the Gardasil HPV vaccine may be fatal for a person who was allergic to dust or mold, which her pediatrician knew she had. You could tell MERCK was at fault by the number of Pharma-trolls that appeared on blog sites. This is a case of the pediatrician burying his mistake, and the medical examiner falsely claiming that the histamine released by eosinophils during an acute allergic reaction was really from an overdose of Benadryl. Death typically occurred within two weeks of receiving the first or second Gardasil HPV vaccine injection.

We observed that children with a (family) history of asthma, pneumonia, or similar pulmonary condition appear to be at acute risk of sudden death where asthma or an exists, an acute release of histamine from eosinophils and mast cells may cause death within hours following following any recombinant vaccine injection such as HebB, MMR, and the Gardasil HPV vaccine. These deaths appear to be related to asthma or an existing or latent (pulmonary) infection, and were documented in both girls and boys, including Michael Fisher. The parents of deceased 15 yr old Michael Fisher with mild asthma reported that he slept approximately 12 to 15 hours after his Gardasil vaccination.   

In rare cases, death has occurred in some, but not all children who reported tiredness (fatigue) immediately following the Gardasil HPV vaccine injection. In the small number of deaths we studied first-hand, we have been unable to confirm the anecdotal deaths of teenage girls who lost consciousness and were killed while driving home after they received the Gardasil HPV vaccination.

In the case of Michael Fisher, slight to moderate exertion appears to result in a life-threatening pulmonary cytokine storm in lung and airway tissue, which appears to be exacerbated by a Gardasil-enhanced hypersensitivity of histamine-producing mast cells and eosinophils. This may produce a foam-like liquid that coats the lungs and airway, preventing oxygen exchange. Vaccine-induced hypersensitivity and inflammation of immune cells in the epithelial lining of lung and airway tissue containing mast-cells may be compounded by a sepsis-like vaccine reaction which may signal an additional release of histamine from mast cells and eosinophils throughout the body. Elevated histamine may acutely dilate blood vessels and lower blood pressure in the host, who may then feel dizzy or "faint" upon standing or even sitting up (Postural Orthostatic Tachycardia Syndrome). The children who acquire Postural Orthostatic Tachycardia Syndrome (POTS) appear more susceptible to sudden death, especially if blood volume declines and they attempt to take a hot shower or bath, resulting in sudden dilation of blood vessels in extremities and possibly life-threatening hypotension and cardiopulmonary events.

UPDATE - October 8, 2014:  The most surprising revelation was that the majority of families in a brief poll revealed that they had Native American (American Indian) ancestors.

 

Four Year Analysis of Adverse Reactions to the Gardasil HPV Vaccine
- Expanded and Updated September 6, 2014 -

by Lloyd W. Phillips

Copyright ©2014 Lloyd W. Phillips

Simplified Version: click here

INTRODUCTION

1) BASIC FUNDAMENTALS OF IMMUNIZATION are being DANGEROUSLY IGNORED

It is well documented that vaccines that use recombinant and synthetic antigens require much stronger adjuvants than whole cell or live cell antigens of the past.  Aluminum adjuvants provide strong immune response stimulation, but have the potential to cause severe local and systemic side-effects. Our purpose here is to observe, document, and categorize the side effects of the Gardasil HPV vaccine and its adjuvant, and provide a plausible explanation of why some people suffer vaccine reactions, including Autism, while others do not.

In the mid 1920s, Ramon et al. noted that horses that developed an abscess at the inoculation site of a diphtheria (toxoid) vaccination, generated higher specific antibody titres. They subsequently found that an abscess generated by the injection of unrelated substances along with the diphtheria toxoid, increased the immune response against the toxoid.

The adjuvant activity of aluminum compounds was demonstrated by Glenny et al. in 1926 with diphtheria toxoid absorbed to alum."  - Immunology and Cell Biology (2004) 82, 488–496; doi:10.1111/j.0818-9641.2004.01272.x

The basic fact that the presence of a pathogen can increase an immune response was discovered by Ramon et al, 1925-26, but it appears to be dangerously overlooked by profit-motivated pediatricians in the 21st Century.  These pediatricians are administering multiple (concomitant) vaccines, some with viruses, which Ramon et al found to cause an increased immune response. 

Clinical trials, such as MERCK's "MOTHER-DAUGHTER INITIATIVE" state that the administration of any other vaccine with the Gardasil HPV vaccine is grounds to EXCLUDE an individual from the Clinical Trial.  In fact, they EXCLUDE anyone who has received a vaccine in the past 30 days.  Merck is well aware that other vaccines with a dead or live virus or bacteria toxoid can enhance the effects of the Gardasil or any other vaccine. Anyone with ANY type of allergy, or who has a compromised immune system, is also EXCLUDED from this Clinical Trial, yet these same people are told by Doctors in the United States that it is perfectly safe for them to receive the same vaccine, and that it has no serious side affects. Every person in our 4+ year study was told this.

2) MEDICAL PROFITS vs. LIFE THREATENING CONDITIONS

We observed the same increased immune response that Ramon et al described in 1925, in virtually all the children and adults we studied (TH2 Dominant).  We discovered that dormant pathogens also appear to enhance the response of aluminum adjuvant vaccines.  We also documented or suspected (multiple) polymorphisms and genetic mutations in these subjects, plus we also noted that a significant number of these children and adults were vaccinated while various stages of a serious infection was present, including pneumonia.  We also discovered that something as common as eczema appeared to be a high risk factor.

The following is from a four+ year study of more than one hundred people who suffered adverse effects from the Gardasil or Cervarix HPV vaccines. All interviews were conducted by direct telephone and/or in-person. 

3) WHAT THESE PATIENTS ARE DEMANDING

The parents and caregivers, and the adults in this study desire share the same goal:  They need knowledgeable medical doctors and additional research to make them well again.

 

DISCUSSION

We identified many variables that make vaccination appear like a roulette wheel, especially in people of Irish, Scotch, English, Swedish, Norwegian, or other Northern or Western European Ancestry, with or without Cherokee Nation  who carry multiple genetic mutations which include the Human Leukocyte Antigen DR15 (HLA-DR15) gene mutation.  This mix of ancestry has also been documented to be associated with the Sickle Cell trait - DOI: 10.1177/000992288702601207.  We noted that facts about vaccines are being withheld from the public, many of which could save lives. We further noted that facts concerning vaccine safety are being dangerously replaced by fraudulent statements for the purpose of defrauding the public and the U. S. Government out of private and taxpayer dollars.  We identified Dr. Paul Offit as a prime example of public deception concerning the safety of vaccines. His statement that 10,000 vaccines (0.5ml per dose) could safely be given to an infant requires that 1.3 U. S. GALLONS (about 5 liters) of fluid be infused into an infant, which would immediately kill the child. Offit's "scientific reference" for his "multiple vaccines are safe" statement is Professor Melvin Cohn, a Theoretical Immunologist, whose ramblings are based on a hypothetically perfect immune system, in a hypothetically perfect body, in a hypothetically perfect environment, receiving hypothetically perfect nutrition, and getting a hypothetically perfect amount of sleep. The sinking of the TITANIC is a good example of Dr. Paul Offit's logic: everything works fine until it meets a Real World iceberg, and two of the big icebergs in Real World medicine are genetic mutations and environmental factors, which can cause the immune system to react unpredicatably.

1) We observed that when a vaccine was given to a child with a dormant or even slightly active infection, the immune system's response to the vaccine was much greater than average. As an example, many children with a history of mononucleosis developed life-threatening reactions.

In the case of a brother and sister who acquired the Gram-Negative Salmonella bacteria from a restaurant weeks before being vaccinated, they both developed seizures almost 3 months to the day after receiving the Gardasil HPV vaccine.  This appears to be a textbook case of the bacteria releasing a Lipopolysaccharide (LPS)-like chemical that appeared to greatly have overstimulated the activity of the immune system when they were vaccinated. The same is true for many pathogens associated with Lyme Disease and it's co-infections.

A vaccine can over-stimulate the immune system in the presence of a Gram-Negative bacterial infection. Bacteria can produce a Lipopolysaccharide(LPS)-like substance that alerts TLR4.  However, some bacterial LPS produced by gram-negative pathogens, especially vector-borne pathogens associated with the Lyme disease family, generate a mutant Lipopolysaccharide that poorly stimulates Toll-Like Receptor 4 (TLR4), which allows these pathogens to "hide" from the immune system (http://www.ncbi.nlm.nih.gov/pubmed/23745121).  [omit in final version-- In-house use only: This fact appears to be withheld by MERCK and other vaccine manufacturers.  We have observed in this study that even dormant pathogens may become virulent as the result of such conditions, and we have hypothesized and directly documented that the antibodies produced may  "hunt down" both SELF proteins (hair keratin, heat shock protein, etc.) and foreign proteins and pathogen(s), such as Bartonella, in tissue and bone throughout the body. This gives the appearance of an autoimmune disease. The majority of the children we observed were seen and misdiagnosed by typically 15 or more doctors.  It appears that when the cause of illness could not be quickly found, due perhaps to the limited knowledge of the attending, these patients were improperly diagnosed with "Conversion Disorder".

Most of these misdiagnosed patients were eventually properly diagnosed and treated only because of the persistence of parents and loved ones, many for Vector-borne pathogens. We observed through interviews and direct contact that the vast majority of doctors are unfamiliar with tests such as Cytokine Panels and PET scans necessary for diagnosing conditions such as Acute Disseminated Encephalomyelitis (ADEM), which we observed in a significant number of subjects. We observed that delays in proper diagnosis and treatment compromise myelin-producing cells, such as Oligodendrocytes surrounded by inflamed glial cells, and caused symptoms found in myelin degenerative disorders.

2) Inflammation caused by the vaccine adjuvant may fail to self-limit, especially if the body fails to clear the aluminum adjuvant in a timely manner.  This overlooked variable may strongly be indicated by such things as abnormal transferrin and / or low ferritin (low iron levels), which may or may not aid the absorption of aluminum. However, we did observe that people in this study group almost always tested low for ferritin (iron).

3) We hypothesize that once inflammation fails to limit or becomes self-sustaining, the demand for raw materials to feed the production of inflammatory cytokines by the immune system, may contribute to unleashing dormant pathogens by tearing apart biofilms and persistor cells, and allowing pathogens to escape and become virulent.

We also found numerous genetic mutations, and must now state that powerful vaccine adjuvants such as Amorphous Aluminum Hydroxyphosphate Sulfate (AAHS), may be life-threatening and/or result in cognitive and motor skill disorders in those individuals with (multiple) genetic mutations which negatively affect or result in:

1) Failure to transport or remove Aluminum Adjuvants and certain metals from the host in a timely manner (such as Low or Mutated transferrin.)

2) Elevated pathogen Load (such as HLA-DR15)

3) Reduced Glutathione or glutathione enzyme activity (such as the GSTM1 polymorphism)

4) Reduced Transsulfuration (such as CBS 699t -- NOTE: These subjects typically suffer excruciating "head pressure" due to sulfur-related compounds, including sulfites, which may pass through the blood brain barrier, and may be the cause of "head banging" in infants and todlers.)

Although other mutations may contribute to the cascade of debilitating events, such as C282Y, which is associated with Hemochromatosis, plus other genes associated with Methylation, the above four genetic conditions formed the core problems in this study.

Syncope / Fainting

We observed that Syncope (fainting), following the Gardasil HPV vaccine, may be the result of an acute allergic reaction -or- a well documented and published non-immunologic reaction to Polyoxyethylene-sorbitan-20-monooleate, which is also known as Polysorbate 80 and Tween 80, which was identified by Coors et al, Ann Allergy Asthma Immunol. 2005 Dec;95(6):593-9, as DIRECTLY being capable of causing severe non-immunologic anaphylactoid reactions. Polysorbate 80 can cause a reaction that is NOT due to an "allergy" but appears to be some kind of chemical reaction. It is well known in emergency pediatric care that when cytokines are released pathologically, Nitric Oxide Synthase (NOS) is produced which induces numerous cells to increase production of Nitric Oxide (NO). NO serves to dilate blood vessels and lower blood pressure. Histamine may also be simultaneously released by eosinophils in response to a severe allergic reaction to components in or relating to the vaccination. We hypothesize that one or more of these reactions that acutely dilate blood vessels may be the cause of these children and adults suddenly losing consciousness after the Gardasil HPV Vaccination. 

Dr. L. C. is a member of our study group. She received the Gardasil HPV vaccine in 2006 while attending medical school.  She returned to class after receiving the HPV vaccine, and lost consciousness. Her vitals were taken, and it was documented that her blood pressure had plummeted to a life-threatening 50/32.  We hypothesize this "fainting" was due to an acute allergy-related response to the yeast and/or other component(s) in the vaccine, which resulted in a massive histamine release from eosinophils and mast cells. This elevated histamine would have quickly dilated blood vessels, and would account for the extreme drop in blood pressure. Eosinophils are capable of releasing 80% of their stored histamine in a matter of minutes. We suspect that these children and adults may not have been properly screened for an allergic reaction as warned in the vaccine package insert, especially an allergy to mold and other members of the Fungal Kingdom. Fortunately for Dr. L. C., she did not drive home after her vaccination and die in a car crash. Warnings were not issued by the FDA until three years later (2009). 

Note: Fewer than 10% of the subjects we interviewed who were severely affected by the vaccine "fainted" after receipt of the vaccine. None of the three families we interviewed whose children died reported that their child fainted immediately following their vaccination.

The UNPREDICTABILITY of Aluminum Adjuvant Clearance from the Human Body
- or -
Why ALL Humans Do Not Suffer Vaccine Injuries and acquire Autism

Noted Geneticist Dr Sin Hang Lee found  HPV16-L1 protein fragments from the Gardasil HPV vaccine tightly bound to their Aluminum substrate (adjuvant) in two different autopsy tissue samples from two different deceased teenage girls. One of the deceased teenagers had received her last Gardasil vaccine injection six months prior to her death. The proprietary HPV16-L1 Protein vaccine fragments were still present in her spleen, causing inflammation and continuing to produce antibodies, which were found nearby. The HPV16-L1 protein fragments were found tightly bound to their aluminum substrates.

Modern Science teaches that aluminum adjuvants separate from vaccine components within about 24 hours of injection. Aluminum has an atomic size of 0.051 nm, with an electrical charge of  +3, and may possibly compete with iron (0.064 nm, +3), magnesium (0.066 nm, +2) or calcium (0.099, +2). About 95% of aluminum binds to transferrin and albumin intravascularly, and is then excreted renally. Transferrin is low when iron is high in the body. Many subjects in our study group tested LOW for transferrin. Some in this group tested positive for Hemochromatosis, with a confirmed positive for an associated C282Y genetic mutation.

We hypothesize that low iron or an iron deficiency or an iron excess may all be an extremely important indication of a possible inability to clear aluminum (adjuvants) from the body of a vaccine recipient, resulting in a possible hyper-activation of the immune system, accompanied by possible failure to properly self-limit inflammation. Simply taking iron supplements before the Gardasil vaccination may result in an inability to properly clear the aluminum vaccine adjuvant because the iron may (partially) saturate transferrin, and not allow it to attract aluminum.

We further hypothesize that numerous genetic polymorphisms or alleles of transferrin such as the common G277S, which results in anemia in a significant number of white women, may be of unsuitable atomic weight or electrical characteristics to efficiently attract and transport various aluminum compounds in all humans ( 2001 Nov;115(2):329-33). Inefficient liver/kidney removal activity may then play a further role in the retention of aluminum adjuvants.  The more vaccines administered, the greater the risk of death from failure of methylation and transsulfuration.

The amount of iron, aluminum, or similar substance taken in that day from antiperspirants, food, or perhaps part of an existing body burden, may act to saturate available transferrin, resulting in inhibited transport and excretion of aluminum, allowing the aluminum from a vaccine to be deposited in tissue, resulting in (possible) symptoms of an iatrogenic autoimmune disease. Additionally, the inflammation resulting from an allergic or other reaction to Gardasil or other concomitant vaccines may be sufficient to induce sequestration of iron and aluminum within cells of the reticuloendothelial system. The spleen is the largest organ in the reticuloendothelial system (a.k.a. mononuclear phagocyte system), and this is the exact place where Dr Sin Hang Lee found mutated HPV16-L1 Protein fragments in autopsy tissue from two deceased teens, long after their HPV vaccinations.

Theobald et al, 1987 Feb;20(1-2):10-6, identified transferrin (TF) as a blocking factor (BF) for histamine in mast cells, but did not reference histamine that may be released by eosinophils in response to an allergic reaction (such as to components in the Gardasil vaccine).  If transferrin is low, the blocking action of histamine is inhibited in a dose-dependant manner (PMID2437773), and this appears to be what we observed, which may partly account for the cascade of debilitating GI events found in these subjects with low transferrin, ranging initially from Histamine Intolerance, Irritable Bowel, and ending up with Gastroparesis. We observe high eosinophil levels in many subjects, long after vaccination. 

Low transferrin, saturated transferrin, or mutated transferrin appears to play a crucial role in the onset of both aluminum adjuvant retention and the manifestation of other conditions, such as Postural Orthostatic Tachycardia Syndrome (POTS).  We hypothesize that transferrin levels, transferrin mutations, and other transferrin anomalies such as molecular weight, play a critical role in regulating histamine release from mast cells in the gut, and thus may be responsible for the severity of such disorders as Irritable Bowel, Celiac, and more.

The inclusion of L-Histidine in the Gardasil HPV vaccine appears to suggest that MERCK Pharmaceuticals is including a pre-cursor to histamine to insure, through decarboxylation, that inflammation and perhaps a localized dilation of blood vessels will ensue upon conversion of L-Histidine to histamine. Unfortunately, the resulting inflammation may provide new host cells (incubators) for an existing or dormant pathogen to invade and multiply.

Based on observation and medical diagnosis of subjects in this well documented study, we find DIRECT parallels with the Autism Community.  While we acknowledge that all cases of Autism are not Iatrogenic, we must disclose that the numerous cascades of metabolic failures due to vaccine adjuvants enhanced by pathogens present in the body, were the root cause of disabling and life-threatening events in people who had already inherited or acquired genetically compromised cycles (methylation, transsulfuration, etc.). We openly state our findings that vaccine adjuvants, especially Amorphous Aluminum Hydroxyphosphate Sulfate (AAHS) may be extremely dangerous and/or life threaten when administered to children and adults with inhibited or mutated transferrin, albumin, or other disruptor which may prolong the retention of inflammation-causing vaccine components, which may result in a myriad of disorders, ranging from inflamed glial cells that may inhibit neighboring Oligodendrocytes from properly producing myelin needed for nerves, which may eventually result in ADEM, Multiple Sclerosis, inhibited cognitive and motor skills, and eventually, death.

It is important to note that while vaccine manufacturers claim that vaccines are safe because they have far less aluminum than the food we eat, ONLY 0.3% of the aluminum contaminants in foods are ever absorbed in the GI Tract, while 100% of the aluminum in a vaccine is put directly into the circulatory system. The body has no known use for aluminum.

Based on our studies with older children and adults, we hypothesize that Infants, especially preemies, with low levels of transferrin or ferritin, are more susceptible to vaccine-induced Autism, because the aluminum vaccine adjuvants do not have sufficient or a sufficiently active form of transferrin and / or ferritin to bind to. Additionally, we question why the host actually stored the HPV16-L1 aluminum protein fragments in autopsied spleen tissue the case of the two deceased teenage girls investigated by Geneticist Dr. Sin Hang Lee.  Huang et al, 1992 and Cannata et al, 1993, found an inverse relationship between ferritin (iron) and aluminum storage in the human body, and virtually all subjects, except those with Hemochromatosis, had low ferritin. Another observation by CANNATI  revealed that the presence, or lack thereof, of iron may influence the absorption and uptake of aluminum by the gut, and we did observe aluminum-containing products such as Tums, and even aluminum based antiperspirants, had a profoundly negative effect on many subjects. We observed that aluminum vaccine compounds were not removed from the body in a timely manner, and appeared free to translocate and damage sensitive neurological centers in the brain. Inflammation appeared to be poorly controlled, and appeared to contribute to cognitive and motor-skill disorders.

We question if the failure of the body to properly and timely clear aluminum adjuvants might be a prime factor in Macrophagic Myofasciitis (MMF).

Enhancement (Hyperactivity) of Immune Activity Due to Infection

In virtually all cases, we observed what appeared to be enhanced adjuvant activity, much of which could be traced back to a Lipopolysaccharide-producing pathogen, such as Salmonella. In the case of brother and sister high school students who both suffered severe reactions to the Gardasil HPV vaccines, unlike the majority, neither child had low NK-CD57 counts. What was unique is that both had became ill after dining at a restaurant, prior to receiving the Gardasil HPV vaccine.  Not only does Salmonella enterica contain immune-enhancing Lipopolysaccharides characteristic of Gram-negative bacteria, it also contains well studied FliC flagillin from the Salmonella enterica, which can modulate an immune response through TLR5 (Hayashi et al., 2001) (Balut et al., 2005) (Nempont et al., 2008). We hypothesize that Salmonella enterica may have played a key role in enhancing the Gardasil HPV vaccine adjuvant activity in these siblings, who both went on to develop seizures 3 months later.

In the majority of other cases, Borrelia burgdorferi or similar Lyme-related co-infection was ultimately diagnosed or suspected. Borrelia burgdorferi, according to various literature, may appear in the L-form as a spirochete or cyst, and both forms exhibit an adjuvant-enhancing Lipopolysaccharide-like substance (lipoprotein) on its outer surface (Schroder et al., 2008) (Thakran et al., 2008) (Yang et al., 2008). Other commonly observed Vector-borne pathogens found in these children and young adults, such as Bartonella, also express immune-enhancing Lipopolysaccharide (Calin et al., 2007; doi: 10.1128/IAI.00237-07), and appear to greatly contribute to the the enhanced and prolonged immune response/disruption.

JAMA reports that the CDC estimates 300,000 cases of Lyme annually (JAMA. 2013;310(11):1110. doi:10.1001/jama.2013.278331). Considering that Lyme (Borrelia burgdorferi) rarely appears without multiple co-infections, and these and other Vector-borne infections, such as Bartonella, Babesia, West Nile, Protozoa Rheumatica, etc., may all appear individually and without the presence of Borrelia, this is opening a potential Pandora's Box of alum vaccine adjuvant unpredictability in the human population.  All of the above named pathogens, and many more, have been diagnosed in this study group.

 Acute Hypotension

Hypotension (and Hypertension) is being reported in a large number in this group. One 14 yr old girl was taken to the hospital after losing conscientiousness at a California ice cream parlor with friends. Vitals and a blood draw were performed at a local hospital, Her blood pressure was documented as 31 systolic over 29 diastolic.  Her pulse rate was 21. Her blood oxygen saturation was 50%.

Acute Hypertension

Hypertension (and Hypotension) are also being reported in a large number in this group, sometimes alternately. A parent of a 12 year old Texas girl attending Henderson Junior High reported that her daughter's blood pressure was recorded at 164 / 130 by the school nurse. Blood pressure deviation(s) should be considered an integral part of this syndrome.

Increased Inflammation and Acute Vitamin D Deficiency ( 25 Hydroxy Vitamin D )

We observed that virtually all who were tested had very low 25 Hydroxy Vitamin D. We observed inflammatory markers such as CRP, IL-1b, TNF-y, etc., which diminished to normal within months in most children, but when the Interleukins were stimulated by LPS, we observed unacceptable counts of approximately 1/4th below acceptable lower gate.

 Aphasia

The majority of people in this group showed varying degrees of difficulty with reading comprehension and recalling common words or names of common objects during conversation.

Muscle Spasms

We have observed what appears to be significant intracellular magnesium depletion so as to result in muscle spasms and heart arrhythmias.

Failure of Immune System and Failure of Body to Repair itself

We acknowledge the award winning work of Stanford Research Biologist Robert Sapolsky regarding stress in primates, and observed that the children and adults in this study appear to be experiencing various degrees of stress so as to inhibit their body's ability to properly fight disease or repair itself. We further hypothesize that vaccine-induced stress may be directly related to Failure To Thrive  in a significant number and may also play a prime role by which autism takes root in infants and toddlers due to inhibiting the immune system and human repair mechanisms, especially during critical developmental stages.

 Sensitivity to MOLD, FUNGUS, and YEAST

A 20 yr old young lady with a known GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTOR (GM-CSF) depletion suffered a cascade of debilitating symptoms when exposed to mold on a couch in a college dorm room.  This does not imply that she was the only one; it simply means that she was one of a few whose GM-CSF was tested and was found to be deficient. GM-CSF has been used successfully as an adjunct to kill fungal infections in cancer patients: http://www.ncbi.nlm.nih.gov/pubmed/8268354

Epstein Barr Virus and Resulting Viral Interleukin-10 as a Risk Factor

We observed that a history of Mononucleosis (Glandular Fever) was virtually a 100% predictor for a life-threatening adverse vaccine reaction, not only to those in our HPV vaccine study group, but to members of other groups we are currently investigating, including those on the Autism Spectrum, and those with Chronic Lyme Disease. We attribute part of this to the ability of the Epstein Barr Virus to produce Viral Interleukin-10 (vIL-10). Viral Interleukin-10 is the product of the Epstein Barr Virus (EBV) replication gene, BCRF1 (Hirokazu et al.).  BCRF1 closely shares functional and structural similarities with Human Interleukin-10. Both viral and human Interleukin-10 inhibit T-Cell growth and interferon-y production. A person who has or recently had EBV may have higher than normal amounts of total Interleukin-10, which may then favor the progression of pathogens and disease.

We found doctors to be generally unreceptive to requests by parents and caregivers of these young children and adults when asked to perform specific tests. We found it was frequently necessary for these ill patients to sometimes travel long distances to find doctors who would even listen to their symptoms and requests. In the case of one 24 yr old Asian girl who had been ill for six years following her Gardasil HPV vaccination, we suggested that she be tested for EBV, based on her symptoms.  When local doctors could not perform the tests we requested through the parent, she was finally properly diagnosed with Chronic Active Epstein Barr Virus (CAEBV) by a doctor in another city. She had fevers and menses approximately two weeks apart for years. Because no doctor had caught this, her mental abilities had declined to the extent that she had to be carefully watched so that she did not hurt herself or her parents, and properly disposed of her waste without playing with it.

Although the CDC released a statement acknowledging 300,000 cases of Lyme each year, we found that 100% of pediatricians who administered the HPV vaccine to these patients and had followed up appared to be unaware of the symptoms of such common infections as Lyme-related infections such as Bartonella (cat scratch fever) and were unable to detect or diagnose Lyme disease. Children such as BrittF, with symptoms consistent with Bartonella and Lyme, were left untreated. We noted that the MAJORITY of people in this study were typically diagnosed at some point with "Conversion Disorder," but were later properly diagnosed, due solely to the persistence of their parents or caregivers.

Allergy to Red Meat


There is a high probability that a serious and potentially life-threatening newly discovered allergy may exist among the children and adults in this study, due to the high percentage who are ultimately diagnosed with Lyme Disease or some of the co-infections normally spread by biting insects and related vectors. It has recently been documented that the bite of a tick or chigger can result in a serious or potentially deadly allergic reaction when red meat is ingested. The allergic reaction has been traced to Galactose-alpha-1,3-galactose, or Alpha-Gal, a type of sugar found in red meat. Red meat includes beef, bison, goat, pork, venison, and other mammals, but not poultry. Unlike peanut allergy symptoms, which occur immediately, allergies to Alpha-gal typically occur hours after eating red meat, and may include, but are not limited to: asthma, anaphylaxis, weakness, nausea, itching, hives, rashes, diarrhea, vomiting, irritable bowel, and much more. . . http://alpha-gal.org/basics/

 

Similarity of Symptoms between HPV Vaccine Reactions and Autism

We observed that 90% of people in this group had a genetic mutation that inhibited the production of Cystathionine Bete-Synthase in the first step of transsulfuration. We further observed that even though the symptoms were similar, they could vary greatly in intensity.  When a symptom was completely missing, such as the 10% of subjects who did not experience severe or sustained head pressure, we suspect that they did not have a particular gene mutation, This head pain was so excruciating in the majority of these children and adults that they became very irritable and forgetful. We hypothesize that the same acute head pressure experienced by these individuals may also be experienced by infants and toddlers, and this severe pain may be the reason they bang their head.

Gibson et al, 2002 May;40(6):493-504.,  discovered that Oxidative Stress was associated with neurodegeneration of cells in the brain and the appearance of a Thiamine deficiency.  We found signs of a Thiamine deficiency in many of these children and adults.

We also noted similarities in vaccine-induced sensitization of immune cells in the lining of the gut and the resulting GI-Tract inflammation, followed by a Histamine Intolerance, and much more.

We hypothesize that inflammation triggered by vaccine adjuvants, and occurring in glial and similar (macrophage) cells may affect surrounding Oligodendrocyte cells, and inhibit the production of the myelin sheath around nerves, resulting in ADEM.

This, plus the Oxidative Stress initiated by vaccine adjuvants, together with genetic mutations that may allow increased pathogens such as Human Leukocyte Antigen (HLA), and specifically the HLA-DR15 allele, together with any current infectious agents already present in the body (such as Mycoplasma, Bartonella, Borrellia burgdorferi, etc.), together with any other contributor which tends to promote or modulate inflammatory cytokines (eczema, acne, etc.), together with any contributor which tends to inhibit or modulate the anti-inflammatory properties of Interleukin-10, may result in Autism in infants and toddlers, and debilitating pathologies in older children and adults. We observed that some primary precepts of immunization are being dangerously overlooked by pediatricians, especially the fact that the presence of an infection during the administration of a vaccine will greatly enhance the immune response (Ramon et al: Bull. Soc. Centr. Med. Vet 1925; 101: 227–34.) -and- (Ann. Inst. Pasteur 1926; 40: 1–1).

We further noted that timely intervention and identification of systemic inflammation was critical. For example, pains in the stomach might soon be followed by IBS, and if the contributing causes, such as a histamine intolerance, were not treated, this might then advance to Gastroparesis. One of the key problems in withholding treatment is the resulting Oxidative Stress, which greatly contributes to a further cascade of debilitating symptoms, especially with its potential to block Thiamine routes.

Dark or Black Menstrual Discharge

To be added

 Chronic/Dominant TH2 - Chronic Production of Antibodies

We hypothesize that a combination of vaccine ingredients, which 1) must be accompanied by the host's compromised ability to limit inflammation due to such thing as an ongoing infection, including eczema, 2) together with the TH2 Causing Polysorbate 80, 3) plus the failure of the host to clear the aluminum based vaccine in a timely manner, resulted in the immune system being forced into a Chronic TH2 Mode. This could help explain the new and increased sensitivities to food and the environment, while increasing Oxidative Stress and inhibiting the body's ability to use Thiamine and possibly other nutrients.

Enlarged Cisterna Chyli

The Cisterna Chyli was found to be enlarged in one girl by an alert radiologist. The size of the Cisterna Chyli was then on used as a gauge for her medical progress. This appears to be valid reasoning because of the involvement of the lymphatic system and elevated lymphs.

Head Pressure (acute)

a). Quick-Onset Head Pressure: Polysorbate 80 - Opening the Pathway to the Brain

We observed that the majority of people in this study group developed severe head pressure, many within the first few hours of receiving the (Gardasil) HPV vaccine.  Only 3 out of about 100 report feeling severe "head pressure in less than an hour after their vaccination, which they described as someone putting their head in a vice and squeezing it. Most reported a pain level of 9 to 10 on a 1 to 10 scale, 10 being the worst.   Those who received concomitant vaccines appeared to have a quicker onset of head pressure and new medical conditions, many after just one HPV vaccination.

We hypothesize that this quick-onset head pressure may be due to factors affecting the integrity of the blood brain barrier, especially the Polysorbate-80 Tween contained within the vaccine, together with both the inflammatory properties of the antigen bound to the aluminum adjuvant, possibly together with the inability of the host to bind to and excrete the aluminum (compromised ability to bind to and transport aluminum, such as compromised transferrin) or sulfur (sulfate) found in the adjuvant, which may be inhibited in part by a genetic mutation negatively affecting Cystathionine Beta-Synthase in the first step of transsulfuration.

According to a Power Point Presentation by Norman W. Baylor, PhD, Director Office of Vaccines Research and Review Center for Biologics Evaluation and Research, Food and Drug Administration, which is available from the FDA website (click here), the aluminum vaccine adjuvant is supposed to be released slowly from the injection site, but many members in our study reported their doctor told them to massage the injection site to decrease pain. In addition, we observed the quick-onset of new medical conditions, especially the commonly described excruciating "head pressure," and question/hypothesize whether or not the Polysorbate Surfactant has / is transforming the Gardasil vaccine components in "Bullet Proteins" which may help to quickly disperse the vaccine, and allow the vaccine to be transported through the blood brain barrier.

b). Chronic Head Pressure

We have observed that Chronic (sustained) head pressure is due to a gene mutation that affects Cystathionine Beta-Synthase (CBS gene) in the first step of transsulfuration. We further confirmed that people with a CBS 699t gene mutation are most seriously affected.  Using the BLAST genetic search tool, we discovered and confirmed that human cell MITOCHONDRIA had similarities to the HPV16-L1 Protein. We hypothesize that a combination of ingredients in the vaccine, especially the Polysorbate 80, together with the failure of the body to properly bind and clear aluminum, or favor aluminum uptake when iron is low (such as found in the majority of people in this study, may act synergistically in (some people) to inhibit mitochondria function, and pervasively inhibit all methylation and other metabolic cycles of the body, which may account for why we observed the proliferation of pathogens in these subjects, especially those with the HLA-DR-15 mutation (AllisonF), who were exposed to the Fungal Kingdom. 

Hypermobility as a Risk Factor

Hypermobility, a symptom of Ehlers-Danlos Syndrome - Type 3, was observed in the majority of our study group.  It should be further noted that follow-up questioning of some of the families who originally reported that their daughter did not have obvious signs of Hypermobility, now stated that siblings of the vaccine-affected child did show signs of Ehlers-Danlos in the form of Hypermobility. (updated: 10-20-2014)

Physical Activity as a Risk Factor for an Adverse Vaccine Reaction

We observed that children who appeared to be VERY healthy prior to receiving the Gardasil HPV vaccine and were the most physically active following the vaccination (heavily used leg muscles and participated in sports, cheerleading, dancing, biking, skating, or other physical activity), suffered the most sever debilitating symptoms, including gait disturbances and an inability to walk, was possibly due to the increased distribution of the vaccine throughout their body due to increased circulation resulting from exercise and a more efficient cardiovascular system. These girls also complained more of chest pain, centered around the heart. Doctors and Hospitals almost universally refused to investigate or follow up on these patient complaints, but instead administered pregnancy and drug tests, before dismissing these patients with a typical diagnosis of "Conversion Disorder".

MichaelF was a 15 yr old male who died a matter of weeks following his Gardasil HPV Vaccination. He died about 15 minutes into an ice-hockey game, and question whether an anaphylactic reaction caused by Polysorbate 80 may have played a role (Coors et al, 2005). We observed that children and adults who appeared to be very healthy may actually have harbored the Human Leukocyte Antigen (HLA) genetic mutation, and the immune system may not have aggressively responded to viruses and other pathogens.  This may have given a false sense of good health, and may actually have allowed the host to harbor high(er) levels of Epstein Barr Virus and other pathogens. A family history of EBV or Mononucleosis/Glandular Fever (full blown EBV) has been virtually a 100% predictor of a severe or life-threatening adverse vaccine reaction in this group. People of Irish descent or similar Northern European ancestry (Scotch, English, Swedes, Danes, etc.) have proven to be the most severely affected.

Transferrin and albumin normally bind to and clear the inflammatory vaccine particles and adjuvant within the vasculature in a timely manner, but when they don't, these particles can settle in tissue or bone, and that may be your reason for reading this Abstract - to find out what went wrong, and how to recover your patient.

According to Kahla et al, 2012, (doi: 10.1590/S1517-83822012000200039. Epub 2012 Jun 1), injecting the Gardasil HPV vaccine into these children and adults, along with the HPV virus-contaminated fragments admitted to by the the manufacturer, MERCK & Co., will increase the risk of (cervical) cancer in the vaccine recipient by 500% in the presence of an Epstein Barr Virus infection.  Kahla et al found that an EBV infection acts as a co-factor for the induction of cervical cancer by favoring integration of HPV DNA.  We observed similar results in a significant number in our study group.

SLEEP and FATIGUE following Vaccination - The First WARNING SIGN of things to come

We observed that some of the first warning signs of impending cascades of debilitating or life-threatening events following the Gardasil HPV Vaccination were excessive sleep and fatigue. In the majority of pre-pubescent subjects, the fatigue remained, but the typical 12 to 16 hours of sleep per day turned into insomnia, with only 2 to 4 hours of continuous sleep per day, usually between 2 and 6 am.  A significant numbers of parents noted a momentary sleep-like state that lasted only a matter of seconds, in which the subject's alert state appeared suspended, and may happen in the middle of a conversation.  The subject would momentarily stop talking with eyes fully open, then resume speaking after several seconds, with no apparent awareness of the gap in their conversation.

Low Vitamin D 

Vitamin D levels appear to plummet (25 Hydroxy Vitamin D) in this group following the administration of the Gardasil HPV vaccination.  Several had been tested months prior to the administration of the HPV vaccine, and lab tests for serum Vitamin D were reported to be within gate. Typical 25 Hydroxy Vitamin D post Gardasil averaged around 20, with some dipping to 12.

Low Intracellular Magnesium

Intracellular magnesium quickly becomes depleted following administration of the Gardasil HPV vaccine. However, serum magnesium typically remained on the low side of lab normal.

Association of Epstein Barr Virus (EBV) and Vitamin E

We observed that many who were tested showed positive for Recent EBV.  We suggested the use of Vitamin E to inhibit EBV in cases of Oxidative Stress, based on the Chen's scientific work Chen et al, 2003 Aug;113(2):228-33, We observed that Vitamin E and the other supplements produced positive results, with fewer and less debilitating flares of symptoms.

Magnesium and the "Fight or Flight" Response in this Group

Our findings indicate that the immune system may not be capable of distinguishing between fear and the inflammation caused by aluminum adjuvants and other ingredients in modern vaccines. Both fear *and* inflammation were observed to trigger the "Fight of Flight" response, which forced the subject to excrete magnesium. 

The human body uses magnesium in the production of about 300 different enzymes. When intracellular (within the cell) magnesium becomes depleted, it is virtually always missed by doctors who look at serum (blood) magnesium. Every cell in the body will contribute its last bit of magnesium to keep the heart pumping. We observed multiple symptoms of a magnesium deficiency: muscle jerks and spasms; pain; irritability; newly acquired panic disorders; heart arrhythmias; headache; and more. One mother described her daughter as the "she bitch from hell" after receiving the Gardasil HPV Vaccine.

Since many cycles fail (methylation, H3K4 Trimethylation, etc.), we observed that it was necessary to administer some vitamins in their active form to maintain proper serum levels. This was especially true of Vitamins B6 and B12.

Similarity to Septic Shock

In the majority of subjects with severe adverse reactions, we observed that the body appeared to pull blood from extremities.

Symptoms of Vitamin B1 Deficiency (Beriberi): Thiamine Tetrahydrofurfuryl Disulfide

Although many of the subjects received Vitamin B1 supplements, we observed many symptoms of a Vitamin B1 (Thiamine) Deficiency. Thiamine is involved in a variety of glucose metabolism-related and neurological functions, including the making of myelin. Many symptoms of the B1 Deficiency decreased when Thiamine tetrahydrofurfuryl disulfide (TTFD) was administered. Allithiamine is one alternative name for TTFD, a fat-soluble form of Vitamin B1.

We acknowledge the observed genetic deficit(s) in the Transsulfuration Cycle due to the CBS gene, and confirm the findings of, DETH R et al, Thomson, and others who documented that oxidative stress plays a critical role in the utilization of Thiamine in the human body.

Hypertelorism (Wide Spaced Eyes)

Mild to moderate HYPERTELORISM (wide-spaced eyes) was observed in virtually all females in this group.

Occurrence of Autism in families with children adversely affected by Gardasil

We observed a correlation among parents of children harmed by the Gardasil vaccine. The siblings of these parents were more likely to have multiple children on the Autistic Spectrum.  We also found that older children in these families, who were not on the autistic spectrum, were less likely to be influenced by environmental factors such as vaccines, such as twin sisters who received Gardasil, where the one with autism suffered an adverse reaction, and the twin without autism did not.

Lymphatic System Impairment

We observed symptoms of impaired Lymphatic drainage, which included, but was not limited to swelling and various skin irregularities, plus elevated body burden, which often included heavy metals. We believe this is primarily the result of lowered or discontinued exercise in these formerly active people, in addition to the lowered blood pressure that was typically observed in these children and adults.

Sisterna Chyli Enlarged

The Sisterna Chyli was found to be enlarged by an alert radiologist. Because this was noted in the medical records of only one young female, and only a minority had imaging tests that would reveal this detail, it is possible that this anomaly of this lymphatic organ may have occurred (at various times) in other subjects. In the case of one young lady, the size of her Sisterna Chyli was inversely proportional to her feeling of well being.

Nosebleeds

Nosebleeds were observed in about half the subjects, post Gardasil. Ferritin (iron), was typically low.

Genetics and Pathogens

The Human Leukocyte Antigen (HLA) Serotype was present in most who were tested. The HLA-DR15 mutation was found in those most seriously affected. Those with HLA-DR15 appeared acutely sensitive to mold, and exposure would cause a re-emergence of debilitating symptoms.

Genetics and Transsulfuration

Many tested positive for the CBS Gene, and were not able to properly process sulfur. The Cystathionine Beta-Synthase gene, especially the CBS 699t genetic mutation, appeared to be causing a life-threatening cascade of events in these patients, and we observed the following sulfur-related symptoms:

Note: Medical Practitioners should be aware that an infant or toddler who screams for prolonged periods, or any child who bangs their head, may actually be signaling that they are experiencing a breakdown in the TRANSSULFURATION Pathway (CBS Gene). When sulfur is not properly metabolized, EXCRUCIATING HEAD PRESSURE may result when sulfites enter the brain and produce acute pain. You should always be on guard that a migraine may be a warning sign of a CBS Gene mutation, especially CBS 699t.

We hypothesize that sulfur-related sustained inflammation, especially involving inflamed glial cells in the brain,  may affect nearby Oligodendrocytes, which may then inhibit myelin production, and result in demyelinating disorders, such as Multiple Sclerosis.

Ovarian Cysts and Cancer in this  Group of HPV Vaccinated Females

We observed that a significant number of females in this group presented with abdominal pain, and many were diagnosed with one or more cysts.  We noted the findings of Sanjib Bhattacharyya et al, 2013 (DOI: 10.1371/journal.pone.0079167) regarding the association of Cystathionine Beta Synthase and Ovarian Cancer, and noted that a significant number of females who were diagnosed with a CBS Gene Mutation, or presented with symptoms consistent with a Cystathionine Beta Synthase gene mutation also  reported various cancers after receiving the Gardasil HPV vaccine, which is advertised as a vaccine to prevent cancer. 

Drug Resistance

We noted that a significant number were resistant to various drugs, and that many in this group had genetic mutations affecting both the Cytochrome P450 pathway and the CBS Gene (Sanjib Bhattacharyya et al, 2013), both of which are capable of affecting drug utilization.

Histamine Intolerance and Sustained Inflammation

We observed that the majority of subjects developed a Histamine Intolerance, which we believe was a direct result of the Aluminum adjuvant in the Gardasil vaccine. The purpose of the aluminum adjuvant is to increase the activity of presenting cells.  We believe that that aluminum adjuvant directly affected and enhanced the activity of presenting cells in the gut, and resulted in new and / or enhanced allergies to food proteins passing through the GI Tract, which then contributed to self-sustaining gut inflammation.  As Mast Cells produced more and more histamine, the subjects acquired a new medical condition known as Postural Orthostatic Tachycardia Syndrome (POTS).  This is a condition in which mast cells produce elevated histamine, which causes blood vessels to dilate in this study group, and resulted in various degrees of light-headedness, disorientation, and increased heart rate, and possible syncope (fainting) upon standing.

There was no reported cases of Histamine Intolerance in any member of this group prior to the administration of the Gardasil HPV vaccine, nor was there any prior indication or family history of Mastocytosis.  We also took note of the extensive research done by Husheng Li et al., at the University of Tennessee, Knoxville, into how aluminum vaccine adjuvants activate caspase-1 and induce an IL-1beta and an IL-18 release, causing inflammation.  We hypothesize that the release of IL-1beta and Interleukin-18 (and possibly other pro-inflammatory cytokines), may have inflamed the gut and caused a breakdown of the mucosal lining. This may have allowed immune cells in the lining of the gut to come into direct contact with food proteins as they traveled through the inflamed gut. The enhanced action of presenting cells and immune cells appear to have made antibodies to some of these food proteins, and when these foods were again eaten at a later date, the hyper-activated presenting cells of the immune system appeared to treat these food proteins as allergens, and trigger mast cells to produce histamine. 

Histamine (elevated) and Blood Vessel Dilation

We observed that the majority of these children and adults felt lightheaded upon standing.  We hypothesize that the elevated histamine, caused by this newly acquired histamine intolerance, dilated blood vessels, and significantly lowered blood pressure to the brain.  We further hypothesize that this may be the cause, or a contributing factor to Postural Orthostatic Tachycardia Syndrome (POTS). We observed that this newly formed histamine intolerance and resulting self-sustaining inflammation did not noticeably subside until foods containing moderate to high amounts of histamine were removed from the diet. We observed that Low Dose Naltrexone appeared to reduce/ eliminate gastrointestinal pain and other negative effects of this condition. Low Dose Naltrexone did not totally eliminate head pain, which we believe is due to an inhibition of the transsulfuration pathway, which allows sulfites to enter the brain.

Acute Disseminated Encephalomyelitis (ADEM)

We observed a significant number of cases of Acute Disseminated Encephalomyelitis, but the true number may never be known due to the unwillingness of competent doctors to order PET Scans, and the ability of patients to pay for these tests which may not be covered by insurance. ADEM can occur in the brain when tissue surrounding myelin-producing cells becomes inflamed, and prevent Oligodendrocytes from doing their job of producing the insulating myelin sheath surrounding nerves.

Ankylosing Spondylitis

Ankylosing Spondylitis was diagnosed in a small but significant number (about 5%) of this study group. The HLA-B27 gene has been associated with Ankylosing Spondylitis, and those that were tested for this gene were positive for this genetic mutation. We hypothesize that the actual number may have been much greater, but when these children and adults are improperly diagnosed with Conversion Disorder, any attempt by parents or caregivers to seek further medical attention appears to have been thwarted.

Sudden Death

and

Sudden Infant Death Syndrome (SIDS)

We further observed that under these conditions, the body appeared to reduce circulation to extremities, leaving the arms and legs of the host feeling cold to the touch, and wanting blankets even on warm days. We further hypothesize that under these conditions, blood volume may be somewhat reduced, and confined mainly to the trunk, especially when lowered salt intake was present. Under these conditions, taking a hot shower may have caused the deaths of several children and adults when extremities were quickly warmed, and blood pressure plummeted due to circulation being restored to these freshly warmed arms and legs, which lowered blood pressure to the heart and brain. Many parents have stated during interview that their child lost consciousness while taking a bath or shower, or shortly thereafter, and we now warn families of the risk of injury from losing consciousness, and the possibility of cardiac arrest.

We hypothesize this (histamine-induced) mechanism that results in sudden lowering of blood pressure in the head and trunk of the body may have already resulted in shock and possibly cardiac arrest in the deaths of several teens. We strongly suggest that medical professionals warn individuals who acquire acute symptoms of POTS or lightheadedness, that they should avoid hot showers and baths.

Astasia-abasia (inability to walk or stand properly)

Astasia-abasia (an inability to stand and/or walk properly) was observed in about 20% of the people in this group at one time or another, typically within days of receiving the HPV vaccine. These children and adults also typically complained about feeling pain in hip joints, which sometimes extend downward through the thigh muscle. About 1 in 20 was confined to a wheelchair for more than one month, while 3 out of a hundred were confined to a wheelchair for at least 6 months.

PCOS and Dysfunctional Uterine Bleeding (DUB) [Heavy and/or Irregular Cycles]

We observed many girls to have heavy and /or irregular cycles. Break-through bleeding was also noted.  In one case, a 24 yr old Asian girl who had been ill since she was in her teens, presented with fevers and 10 day cycles. She was subsequently diagnosed with Chronic Active Epstein Barr Virus (CAEBV), and was the only one in the group of over 100 to be diagnosed with EBV in the chronic form.  Titers were 10x gate. 

A significant number of other young girls were eventually diagnosed with newly acquired PCOS. Many girls were placed on oral birth control in an attempt to regulate periods and flow with generally negative affects. Many of these girls then presented with a raised, bumpy rash, mainly on the trunk of the body, which sometimes extended to the face and ears. This hive-like rash typically appeared within one to three days of ingestion of oral birth control. 

Polio-like Symptoms, Flaccid Paralysis

Greater than 10% of these children and adults presented with symptoms typically associated with Polio. Many were confined to a wheelchair for extended periods. These symptoms require much greater study, which is far beyond our capacity.

Innate Lymphoid Cells

We strongly suggest further investigation into Innate Lymphoid Cell Groups, especially ILC2, which is associated with parasites.

Allergies to CITRIC ACID in foods, soft drinks, preservatives, etc.

We observed that new and increased sensitivities to mold and members of the Fungal Kingdom was common. We hypothesize that due to the failure of the host to timely clear the vaccine and its inflammatory payload, the host not only formed antibodies to the HPV Proteins in the vaccine, but also appeared to form aggressive antibodies to fungus (the HPV vaccine proteins are grown in a fungus). We further observed and investigated what turned out to be a related phenomenon. Because of this new or enhanced sensitivity to fungus, many of these children and adults now responded acutely to anything that contained citric acid, including the minute level of citric acid preservative found in a power-bar. After a lengthy investigation, we found that virtually all citric acid sold in the United Stated was manufactured synthetically by means of fermentation, and the favorite fermenting agent was Aspergillus Niger, a cousin to the fungus in the Gardasil HPV vaccine.  By putting 10,000 gallons of corn oil or similar sugar-rich base in a vat, then adding Aspergillus Niger (black mold) and waiting a while for it to ferment, you didn't have to use lemons, limes, etc., or have to worry about citrus crop failures, or clean up peels, seeds, or leaves.  You just had to filter out the mold at the end of the fermentation process... * BUT * .. you can't filter out the MYCOTOXINS. Mycotoxin exposure most logically explains what was causing many patients to experience a re-emergence of debilitating gastrointestinal and auto-immune symptoms. Whenever they ingested this commercially-made citric acid, many had varying degrees of adverse reactions, some lasting for days.

Symptoms of Pericarditis

We observed that the majority of people with Astasia-abasia also complained of heart pain.  They described it as feeling that someone was squeezing their heart. We suspect this may be due to Pericarditis or possibly Pericardial Effusion. 

In the remainder of the group whose gait was not severely affected, only about 1 in 10 complained of heart pain.  We hypothesize that since the heart muscle and pericardium may have a higher sensitivity to elevated levels of homocysteine (Jhee et al, 2005, doi:10.1089/ars.2005.7.813), the risk of cardiovascular events and /or death may increase due to a further elevation of homocysteine resulting from inhibited transsulfuration.

Hair Loss - (antibodies to Hair Keratin, Mitochondria, and Heat Shock Protein)

Virtually all girls in this study reported varying degrees of hair loss, especially after baths, showers, and brushing their hair.  I used the BLAST genetic database search engine against the Swiss Database to determine similar proteins to the HPV16-L1 protein to which the human immune system might respond.  There was a 99.9% match to the Rhesus Monkey Papilloma Virus Type 1, and approximately a 30% match to human hair keratin.  Hair loss appeared to peak about 1 - 2 years after the first Gardasil vaccination.  In addition to HAIR KERATIN, the antibodies produced against the HPV16-L1 Protein in the Gardasil HPV vaccine also negatively impacted Mitochondria, Heat Shock Protein, and more. Heat Shock Proteins are strongly associated with the cardiovascular system, cancer, and the immune system. Schlesinger et al, 1990, reveals that heat Shock Proteins are also signaled in response to heavy metals. We observed elevated metals in many of these subjects, including but not limited to: nickel, aluminum, and copper (Pyroluria was diagnosed in a small percent).

Abortion

Of the girls in this study who became pregnant after suffering adverse effects as a result of the Gardasil HPV vaccination, approximately 30% reported miscarriages. We hypothesize that increasingly elevated homocysteine levels and decreases in Interleukin-10 may be responsible for the abortive effects associated with the Gardasil HPV vaccine. Cystathionine Beta-Synthase expression (production) appeared to decrease due to the resulting inflammation caused by the onging (hyper) active immune response, which then resulted in elevated homocysteine. Elevated homocysteine has been associated with terminated pregnancies. The decreased transsulfuration observed in many of these subjects may result in decreased glutathione activity and a further increase in inflammation, plus a suspected decrease in Interleukin-10, an anti-inflammatory cytokine normally elevated during pregnancy. Decreased Interleukin-10 availability in the human body may help sustain inflammation and cause the fetus to be wrongfully recognized as foreign, rather than "self".

Disparity in Medical Treatment Involving Race and Age of Patients Presenting to Emergency Clinics and Hospitals

JanaW is Afro-American and has a 13 yr old daughter injured by the HPV2 vaccine (Cervarix). JanaW was told NOT to come back or send her sick child to her pediatrician's office after her daughter suffered a sever and life-threatening vaccine reaction to the CERVARIX HPV vaccine.  We noticed a significant disparity of treatment involving age and race of the child.  In the case of JanaF, she asked a hospital for an MRI to be done for her 13 yr old daughter, but was told it was too expensive.  This did not appear to be a significant problem if the child was white.  We observed that females between the ages of 13 and 17 were most likely to have their symptoms ignored.

Children such as MeganF, would present to doctors and emergency departments over and over with the same complaints, and were dismissed after the usual pregnancy and drug tests. 15 yr old MeganF was later found by another hospital to have a fairly large ovarian cyst that her Dublin Georgia hospital had ignored, and the red patches of skin on her body was not a sunburn, it was a rash.

Conversion Disorder

We observed that the MAJORITY of the children and adults were negligently misdiagnosed with "Conversion Disorder".  We observed that 100% of these people were suffering from a treatable disease, and the misdiagnosis of CONVERSION DISORDER was responsible for the worsening of their condition. The majority of subjects were typically seen by 15 or more doctors and specialists in both private practice or hospital settings.   The average person had 10 or more visits to emergency departments, mostly for pain, breathing, or heart-related issues.

Placebo Effect

We observed this group to be very susceptible to the Placebo Effect, and offer the following explanation:  Since one of the key signatures of this syndrome is oxidative stress, we hypothesize that any reduction in stress, including simply thinking or hoping that a pill or treatment will work, may have a relaxing effect upon the patient that may reduce oxidative stress, which may then result in the reduction of adrenaline, cortisol, and the production of pro-inflammatory cytokines.  For this reason, the subject's immediate health may appear to improve, even if the treatment may later prove to be harmful.

 Cortisol

We observed cortisol to typically be low in the morning, with some of the more seriously affected presented with symptoms of elevated cortisol as the day progressed. We observed that the children with the highest cortisol levels (greatest oxidative stress) presented with symptoms similar to Addison's and/or Cushing's Disease. Those with the highest cortisol levels (stress) also appeared to exhibit the most belly fat, We suggest the use of Vitamin C (Berry Boost® or other 100% FRESH fruit juice) with each meal to inhibit the body's ability to produce stress hormones.

Insomnia

Insomnia was present in the majority of the subjects.  We attribute this (in part) to the pineal gland possibly being inhibited by cortisol which was released in response to inflammation, including inflammation associated with the newly acquired histamine intolerance.  In addition to mitigating Histamine Intolerance, we observed that Low Dose Naltrexone also helped to relieve insomnia, allowing for approximately five hours of uninterrupted sleep.

Pathogens and Body Burden

(a) Enteroviruses

The most common enterovirus we observed was Epstein Barr Virus (EBV).  EBV was shown to act as an incubator for other pathogens and infect fast-growing cytokines when inflammation is present. A previous history of Mononucleosis (Glandular Fever) was virtually a 100% predictor of a life-threatening adverse reaction to the Gardasil HPV vaccine, and similar results were observed among families of autistic children. The antiviral, Famvir, has shown to be safe and effective in a small, but significant number.

Only one out of approximately 100 families observed or interviewed was eventually diagnosed with Chronic Active Epstein Barr (CAEBV), characterized by 10-14 day menses, accompanied by fever.

(b) Parasites

Vector borne pathogens such as Bartonella, Borrelia Burgdorferi (Lyme Disease), Mycoplasma Pneumoniae, Babesia, and FL1953 (Protomyxzoa Rheumatica), were the most commonly observed pathogens. Several would typically be found together in the children who were tested. Bartonella was never found alone.

Note: NK-CD57 counts typically ranged between 8 and 51, with the majority falling at or below 22.

(c) Bacteria

A history of Mononucleosis (Glandular Fever), Mycoplasma/Mycoplasma Pneumoniae, Acne Vulgaris (which can turn Interleukin-10 into Viral Interleukin-10 (vIL10)), and eczema were identified as risk factors for a severe adverse reaction. Interleukin-10 is associated with controlling inflammation.

RASHES

(a) Livedo Reticularis

Livedo Reticularis is a purplish lace-like "rash" that appeared on the body of a significant number of subjects subjects in this study group.  Several were diagnosed with Anti-Phospholipid Syndrome, but none with Sneddon's Syndrome. Because virtually all members of this group were of Western European Ancestry, we acknowledge the possible presence of Mutations in the medium chain acyl-CoA dehydrogenase (MCAD) gene as described by Tanaka et al, ( 1992;1(4):271-9), which results in an MCAD deficiency.

In addition to the possible presence of the MCAD gene and Anti-Phospholipid Syndrome, we hypothesize that the manifestation of Livedo Reticularis in these children and adults may also be associated with the Lupus-like symptoms we observed, and may also be the result of a combination of elevated histamine combined with the inhibited removal of calcium from the circulatory system (a form of Calciphylaxsis) due to contributing factors which include, but are not limited to: 1) Low Vitamin D; 2) Low Intercellular Magnesium; 3) Low Vitamin K2. 

We believe that the dilation of blood vessels and capillaries by histamine contributes to lowered blood flow and blood pressure, which may aid the retention of calcium and other materials in the lining of blood vessels. To prove this hypothesis, we suggested the daily administration of 5,000 iu vitamin D, together with 150 milligrams Magnesium Glycinate twice daily, plus 45 micrograms of Vitamin K2 in the form of Menaquinone, which reportedly also serves as a neuroprotector. Some caregivers later reported that the Livedo Reticularis had improved. We further believe that malabsorption and / or nutrient depletion played a key role.

(b) Hives

Hives were common among this group, and may be the result of elevated histamine production and / or a failure of the body to regulate and eliminate histamine.

(c) Molluscum Contagiosum

Molluscum Contagiosum, a contagious but benign viral disease of the skin, has been observed and medically diagnosed in some members of this study group. The raised bumps that appear may also be called "water warts", were typically not painful. They appeared from the face to the genitals, and may be mistaken for genital warts. We question if MERCK Pharmaceuticals is taking advantage of this similarity when promoting their Gardasil HPV vaccine against genital warts.  The Gardasil HPV vaccine WILL NOT prevent this type of infection, and we observed the Gardasil HPV vaccine appeared to make the condition worse in these immunocompromised individuals. We further believe that vaccinating a person with Molluscum Contagiosum will result in a severe adverse vaccine reaction to that individual.

(d) Henoch–Schönlein Purpura (HSP)
  a.k.a. Schönlein–Henoch Purpura, Anaphylactoid Purpura, and Purpura Rheumatica

(in progress)

Phantom Tremors

A significant number of children and adults reported feeling a tremor sensation in extremities, especially hands and forearms, but neither they nor the people around them could detect any movement.

Eczema, Acne, and Related Rashes as Risk Factors

Many of the children and adults developed an acute eczema-like rash on their face within weeks of receiving the Gardasil HPV vaccination. Many of these children had Acne or eczema prior to receiving the HPV vaccine, but a minority reported that they did not.  Rashes appear to be a risk factor for a serious adverse vaccine reaction if  present prior to a vaccination, possibly due to the ability of some infections, such as Acne Vulgaris, to not only make the immune response more aggressive, but also to promote the production of viral Interleukin-10 (vIL-10). Excessive total IL-10 has been shown to promote pathogens, and we did observe numerous pathogens in many of these subjects.

Interstitial Cystitis

A significant number of female subjects developed Interstitial Cystitis (IC) many months after they appeared to significantly recover from adverse affects of the Gardasil HPV vaccine. Interstitial Cystitis appeared with an acute 25 hydroxy vitamin D deficiency and seemed to coincide with peak antibody production of approximately 12 to 24 months after receiving the first HPV vaccine injection, which initiates inflammation in the body. In at least one case, a non sexually active female in her mid 20s reported no other adverse symptoms except for Interstitial Cystitis (IC). Recent 2014 findings associate IC with a 1.25 di-hydroxy vitamin D3 deficiency.

Need for specialized testing after vaccination

Upon closer examination, it was found that a COMPREHENSIVE CYTOKINE PANEL would have uncovered the underlying inflammation if the attending professional would have observed LPS Stimulated Cytokine counts, which we found to be typically 25% below the lowest acceptable lab levels (lower gate). Additionally, virtually all of the subjects who were tested had NK-CD57 absolute counts falling between 8 and 22, instead of the "lab normal" range of 63 to 360 counts (LabCorp #505026; HNK1 CD57). It is important to note that "Conversion Disorder" in these numerous cases was a costly misdiagnosis for these children and adults, and the loss of time before proper treatment and diagnosis resulted in further failure of methylation cycles and transsulfuration, and only contributed to further nerve damage, such as the demyelization resulting from the inhibition of myelin-producing Oligodendrocytes due to inflammation from surrounding glial cells.

Gardasil HPV may actually Increase Cancer Risk

We observed that the Gardasil vaccine (and possibly others), can disrupt methylation cycles by initiating inflammation that fails to properly self-limit in some individuals.  We observed this this long-term inflammation produced symptoms of oxidative stress.  Kassner et al, 2013  ( 2013 Oct 2;3(10):120173. doi: 10.1098/rsob.120173) demonstrated that disruption of certain areas of methylation can disrupt the production of poly-ADP-ribose formation due to oxidative stress. Poly(ADP-ribose) polymerase-1 (PARP-1) is a member of the PARP enzyme family and contributes to DNA repair and genomic stability, according to László Virág et al, 2002  (Pharmacological Reviews vol. 54 no. 3 375-429).  László also confirmed that overexpression, due to oxidative stress, culminated in cell dysfunction or necrosis, and further stated that "This cellular suicide mechanism has been implicated in the pathomechanism of stroke, myocardial ischemia, diabetes, diabetes-associated cardiovascular dysfunction, shock, traumatic central nervous system injury, arthritis, colitis, allergic encephalomyelitis, and various other forms of inflammation." 

We hypothesize that inhibition of this and other methylation cycles, such as H3K4 trimethylation, may also contribute to mutations and malignancies by inhibiting the production of Semaphorin 3F and others, which may be responsible for the identification and destruction of corrupted DNA that is beyond repair.

Based on the debilitating flares of sustained inflammation found in these formerly atypical children and adults following administration of the Gardasil HPV Vaccine, we believe that the Gardasil vaccine (and possibly other vaccines) was the proximate cause of the debilitating disorders and associated cancer-related conditions found in a significant number of these children. We also note that the susceptibility for cancer is heightened in the group we observed because of the combination of the inflammation initiated or enhanced by the HPV vaccine, together with the presence of EBV.  We also call attention to Epstein–Barr nuclear antigen 1 (EBNA1), which is a multifunctional, dimeric viral protein associated with Epstein–Barr virus (EBV) (Humme et al, 2003). EBNA1 is the only EBV protein found in all EBV-related malignancies. (Duellman, 2009), (Young et al, 2004)

Kahla et al, 2012, observed that the HPV16 virus by itself is not significant enough to cause cervical cancer, but adding EBV to the equation increased the chance by 500%.  Many of these children and adults were positive for EBV.

Conclusion: In a significant number of children and adults, the HPV Vaccine may actually be responsible for causing debilitating disorders and malignancies by initiating sustained inflammation.  Because the HPV vaccine can reactivate viruses and pathogens, including those associated with encephalitis (especially HHV6) and Lyme Disease (Bartonella, etc.), it is well documented in MERCK's PDR that up to 70% of the related encephalitic conditions (and the possible resulting inflammatory-related malignancies) may occur years later (click for PDR reference). This helps account for vaccine-delayed injuries.

One last finding is a confirmation of the work of Jill James et al (doi: 10.1007/s10803-008-0591-5), who discovered that the parents of autistic children suffered from gene mutations that involved abnormal methylation and transsulfuration.  We found similarities in parents and children in this study. We find that the Gardasil HPV vaccine caused the inflammation that resulted in virtually the same symptoms found in autistic children, confirming a direct link between failure of both methylation genes and transsulfuration gene mutations, such as CBS-699t.  These numerous HPV vaccine victims confirm a direct link between vaccines and the disruption of the same or similar cognitive and motor skill functions found in autism, especially those related to metabolism and methylation: http://ajcn.nutrition.org/content/80/6/1611.full

 

 


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The Untold Story About the Gardasil HPV Vaccine


***** CONTACT THE FDA WITH YOUR STORY ***** SHARE *****

Please write an email to the FDA and let them know how Gardasil, Cervarix, or another vaccine, given alone or with something else, has affected you or your child. Send your story to Lorrie McNeill: OCOD@FDA.HHS.GOV 

If you leave something out the first or second time, send the whole story over again. Unless you formally submit your story to this specific FDA Government email address, the FDA may not formally investigate or acknowledge that your child has been injured. Please include a telephone number and address where you can be reached.


Every drug that has ever been recalled, has been proven to be safe and effective by the FDA

After World War II, United States President Dwight D. Eisenhower warned of an industrial military machine influencing and manipulating the United States Government and its elected officials. In today's world, the military machine has been replaced by something far worse: The Pharmaceutical Industry.

 

intermittent exotropia / aphasia / auditory processing disorder / "dog" test / ASM = speaker in the ear   "immature hearing pathway"

 

OLD INTRODUCTION

We are now able to document the conditions which cause the majority of cases of Autism in the United States, along with many other neurodegenerative disorders, especially those associated with vaccines. We acknowledge that an extremely rare group of inherited genetic mutations may actually be responsible for some extremely rare cases of ASD, but the vast majority are iatrogenic.

Diseases such as shigellosis, Lyme Disease and its multitude of co-infections, and/or other infectious pathogens that initiate inflammation, may contribute to or help initiate the type of prolonged inflammation that results in this Syndrome. The removal of minerals from municipal drinking water, especially magnesium, may further contribute to disease and autism by contributing to a deficit in enzymes, hormones, and other metabolic products needed to thrive. However, we have observed that vaccination is the primary cause of Autism (ASD) and other debilitating disorders because of the prolonged oxidative stress it can elicit. This forced activation of the TH2 component of the immune system may result or contribute to a hyper-sensitization of immune cells in the the human body. This hyper-sensitization, especially of T-cells in the epithelial lining of the gut which processes food, may result in food allergies and food intolerance, which may ultimately result in cascades of debilitating events due to the disruption of nutrient absorption, metabolism, and cycles of the human body such as methylation and transsulfuration. We further observed that the human body can inhibit thiamine uptake, excrete magnesium, and inhibit 25 hydroxy vitamin D production during oxidative stress. We identified thiamine deficiency as one of the chief nutritional deficiencies. We observed that this thiamine deficiency may be overcome by the administration of Thiamine Tetrahydrofurfuryl Disulfide (TTFD), the fat soluble form of thiamine.

Update - August 3, 2014: We are now receiving reports that (many) children and adults who originally reported no adverse effects from the HPV vaccine have now acquired new or increased food allergies and sensitivities, years after their vaccination. Some have reported seizures two years later.

 

Americans pay at least 200 to 300 percent more for all drugs

By Law (passed by Congress), MEDICARE must pay the full price of whatever a drug company asks, while other Governments negotiate

At one point, SANOFI told Cancer Doctors (Oncologists) to:
Sell ZALTRAP to the cancer patient for $11,000.00 per month and we'll send you a check (kickback) for $6,000.00

GLEEVEC cancer drug extends life by about 10 years, and cost $28,000.00 in 2001.
GLEEVEC sells for $96,000.00 in 2015